4-Chloro-2-fluorobenzenesulfonamide

Base Information

Chemical Name:4-Chloro-2-fluorobenzenesulfonamide
CAS No.:852664-20-1
Molecular Formula:C₆H₅ClFNO₂S
Molecular Weight:209.629
Hs Code.:
European Community (EC) Number:823-231-6
Mol file:852664-20-1.mol

Synonyms:4-chloro-2-fluorobenzenesulfonamide;852664-20-1;4-chloro-2-fluorobenzene-1-sulfonamide;4-Chloro-2-fluoro-benzenesulfonamide;SCHEMBL2774927;HMS1768G18;CJB66420;GS0296;MFCD06677156;AKOS000137913;SB78489;EN300-55227;Z45415631

Suppliers and Price of 4-Chloro-2-fluorobenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-chloro-2-fluorobenzene-1-sulfonamide
250mg
$ 265.00

Crysdot
4-Chloro-2-fluorobenzenesulfonamide 95+%
5g
$ 629.00

AK Scientific
4-Chloro-2-fluorobenzenesulfonamide
10g
$ 1670.00

Total 1 raw suppliers

Chemical Property of 4-Chloro-2-fluorobenzenesulfonamide

Chemical Property:

PSA：68.54000
LogP:2.90760
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:208.9713554
Heavy Atom Count:12
Complexity:251

Purity/Quality:: 4-chloro-2-fluorobenzene-1-sulfonamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Cl)F)S(=O)(=O)N

Technology Process of 4-Chloro-2-fluorobenzenesulfonamide

There total 3 articles about 4-Chloro-2-fluorobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 852664-20-1
4-chloro-2-fluorobenzenesulfonamide

Guidance literature:: With ammonium hydroxide; In methanol; at 20 ℃; for 16h;

Reference yield:

: 57946-56-2
2-fluoro-4-chloroaniline

: 852664-20-1
4-chloro-2-fluorobenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; sulfur dioxide; copper dichloride; hydrogenchloride; sodium nitrite / water / 0.25 h / -5 °C

2: ammonia / water; 1,4-dioxane / 30 h / Cooling

With hydrogenchloride; sulfur dioxide; ammonia; acetic acid; copper dichloride; sodium nitrite; In 1,4-dioxane; water;
DOI:10.1021/jm501268r