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CAS

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141337-26-0

4-Chloro-2-fluorobenzenesulfonyl chloride, also known as 4-chloro-2-fluorobenzene-1-sulfonyl chloride, is an organic compound characterized by its sulfonyl chloride functional group. It is a derivative of benzene with a chlorine atom at the 4th position and a fluorine atom at the 2nd position, attached to a sulfonyl chloride group. 4-CHLORO-2-FLUOROBENZENESULFONYL CHLORIDE is known for its reactivity and is commonly utilized in the synthesis of various organic molecules, particularly in the pharmaceutical and chemical industries.

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  • 141337-26-0 Structure

  • Basic information

    1. Product Name: 4-CHLORO-2-FLUOROBENZENESULFONYL CHLORIDE
    2. Synonyms: 4-CHLORO-2-FLUOROBENZENESULFONYL CHLORIDE;4-CHLORO-2-FLUOROBENZENESULPHONYL CHLORIDE;Benzenesulfonyl chloride, 4-chloro-2-fluoro- (9CI);4-Chloro-2-fluorobenzenesulphonyl chloride 97%;4-Chloro-2-fluorobenzenesulphonylchloride97%;2-Fluoro,4-chloro benzene sulfonul chloride;4-chloro-2-fluorobenzene-1-sulfonyl chloride;4-Chlor0-2-Fluorobenzen sulfonyl chloride
    3. CAS NO:141337-26-0
    4. Molecular Formula: C6H3Cl2FO2S
    5. Molecular Weight: 229.06
    6. EINECS: N/A
    7. Product Categories: SULFONYLHALIDE;Aromatic Halides (substituted);Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds
    8. Mol File: 141337-26-0.mol

  • Chemical Properties

    1. Melting Point: 34-38 °C(lit.)
    2. Boiling Point: 257.4±20.0℃ (760 Torr)
    3. Flash Point: >230 °F
    4. Appearance: /
    5. Density: 1.610±0.06 g/cm3 (20 ºC 760 Torr)
    6. Vapor Pressure: 0.0234mmHg at 25°C
    7. Refractive Index: 1.55
    8. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    9. Solubility: N/A
    10. Sensitive: Moisture Sensitive
    11. CAS DataBase Reference: 4-CHLORO-2-FLUOROBENZENESULFONYL CHLORIDE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 4-CHLORO-2-FLUOROBENZENESULFONYL CHLORIDE(141337-26-0)
    13. EPA Substance Registry System: 4-CHLORO-2-FLUOROBENZENESULFONYL CHLORIDE(141337-26-0)

  • Safety Data

    1. Hazard Codes: C
    2. Statements: 34
    3. Safety Statements: 26-36/37/39-45
    4. RIDADR: UN 3261 8/PG 2
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: 8
    8. PackingGroup: II
    9. Hazardous Substances Data: 141337-26-0(Hazardous Substances Data)

141337-26-0 Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-2-fluorobenzenesulfonyl chloride is used as a synthetic intermediate for the production of [1-(4-chloro-2-fluorophenylsulfonyl)piperidin-4-yl] diphenylmethanol. 4-CHLORO-2-FLUOROBENZENESULFONYL CHLORIDE serves as a key component in the development of pharmaceuticals, potentially contributing to the creation of new drugs with specific therapeutic properties.
The application of 4-chloro-2-fluorobenzenesulfonyl chloride in the pharmaceutical industry is primarily due to its ability to react with various functional groups, allowing for the formation of diverse molecular structures with potential medicinal applications. Its unique combination of chlorine and fluorine atoms, along with the sulfonyl chloride group, makes it a valuable building block for the synthesis of complex organic molecules with specific biological activities.

Check Digit Verification of cas no

The CAS Registry Mumber 141337-26-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,3,3 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 141337-26:
(8*1)+(7*4)+(6*1)+(5*3)+(4*3)+(3*7)+(2*2)+(1*6)=100
100 % 10 = 0
So 141337-26-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H3Cl2FO2S/c7-4-1-2-6(5(9)3-4)12(8,10)11/h1-3H

141337-26-0 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
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  • Detail

  • Alfa Aesar

  • (L19882)  4-Chloro-2-fluorobenzenesulfonyl chloride, 99%   

  • 141337-26-0

  • 1g

  • 338.0CNY

  • Detail

  • Alfa Aesar

  • (L19882)  4-Chloro-2-fluorobenzenesulfonyl chloride, 99%   

  • 141337-26-0

  • 5g

  • 1238.0CNY

  • Detail

  • Aldrich

  • (555983)  4-Chloro-2-fluorobenzenesulfonylchloride  97%

  • 141337-26-0

  • 555983-1G

  • 471.51CNY

  • Detail

  • Aldrich

  • (555983)  4-Chloro-2-fluorobenzenesulfonylchloride  97%

  • 141337-26-0

  • 555983-5G

  • 1,633.32CNY

  • Detail

141337-26-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Chloro-2-fluorobenzene-1-sulfonyl chloride

1.2 Other means of identification

Product number -
Other names 4-Chloro-2-fluorobenzenesulfonyl chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:141337-26-0 SDS

141337-26-0Upstream product

141337-26-0Relevant articles and documents

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Francotte, Pierre,N?rholm, Ann-Beth,Deva, Taru,Olsen, Lars,Frydenvang, Karla,Goffin, Eric,Fraikin, Pierre,De Tullio, Pascal,Challal, Sylvie,Thomas, Jean-Yves,Iop, Fabrice,Louis, Caroline,Botez-Pop, Iuliana,Lestage, Pierre,Danober, Laurence,Kastrup, Jette S.,Pirotte, Bernard

, p. 9539 - 9553 (2015/01/09)

Two 4-ethyl-substituted pyridothiadiazine dioxides belonging to α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor positive allosteric modulators were cocrystallized with the GluA2 ligand binding domain in order to decipher the impact of

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Substituted sulfonamides, process of preparation and medicines containing same

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, (2008/06/13)

The present invention concerns new substituted sulfonamides, and the physiologically acceptable salts possibly in the form of complexes, esters and amides thereof, represented by the formula: STR1

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