2-Hydroxy-5-methyl-4'-chloroazobenzene

Base Information

• Chemical Name: 2-Hydroxy-5-methyl-4'-chloroazobenzene
• CAS No.: 2491-56-7
• Molecular Formula: C13H11 Cl N2 O
• Molecular Weight: 246.696
• NSC Number: 85565
• Nikkaji Number: J71.635I
• Mol file: 2491-56-7.mol

Synonyms:2491-56-7;2-Hydroxy-5-methyl-4'-chloroazobenzene;NSC85565;NSC 85565;NSC-85565;STL299967;4'-chloro-2-hydroxy-5methylazobenzene;AKOS003416869;2-[(4-chlorophenyl)azo]-4-methylphenol;2-[(E)-(4-chlorophenyl)diazenyl]-4-methylphenol

Chemical Property of 2-Hydroxy-5-methyl-4'-chloroazobenzene

Chemical Property:

• Vapor Pressure: 5.73E-06mmHg at 25°C
• Boiling Point: 379.7°Cat760mmHg
• Flash Point: 183.5°C
• PSA: 44.95000
• Density: 1.23g/cm³
• LogP: 4.76940
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 246.0559907
• Heavy Atom Count: 17
• Complexity: 264

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)O)N=NC2=CC=C(C=C2)Cl

Technology Process of 2-Hydroxy-5-methyl-4'-chloroazobenzene

There total 5 articles about 2-Hydroxy-5-methyl-4'-chloroazobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

4-methyl-2-nitrophenol (119-33-5) → 2-(4-Chloro-phenyl-NNO-azoxy)-4-methyl-phenol + bis-(4-chloro-phenyl)-diazene (1602-00-2) + 2-(4'-chlorophenylazo)-4-methylphenol (2491-56-7)

Guidance literature:

at 55 ℃; for 3h;

DOI:10.1246/bcsj.62.1621

Reference yield: 20.0%

4-methyl-2-nitrophenol (119-33-5) → 2-(4-Chloro-phenyl-NNO-azoxy)-4-methyl-phenol + 5-(4-Chloro-phenylamino)-4-methyl-2-nitro-phenol + bis-(4-chloro-phenyl)-diazene (1602-00-2) + 2-(4'-chlorophenylazo)-4-methylphenol (2491-56-7)

Guidance literature:

at 55 ℃; for 3h;

DOI:10.1246/bcsj.62.1621

Reference yield:

p-cresol (106-44-5) + p-chlorobenzenediazonium chloride (2028-74-2) → 2-(4'-chlorophenylazo)-4-methylphenol (2491-56-7)

Guidance literature:

With alkali;

upstream raw materials:

p-cresol

p-chlorobenzenediazonium chloride

4-chloro-aniline

4-methyl-2-nitrophenol

Downstream raw materials:

4-acetoxy-3-(4-chloro-phenylazo)-toluene

bis(2-{4-chloro-benzeneazo}-1-hydroxy-4-methyl-benzene)-cobalt(II)

{Cu(C₆H₄ClNNC₆H₃(CH₃)(O))2}

Os(P(C₆H₅)3)2Br(ClC₆H₃N₂C₆H₃(CH₃)O)