BenzeneMethanol, α-(aMinoMethyl)-α-(4-chlorophenyl)-4-(1H-pyrazol-4-yl)-

Base Information

Chemical Name:BenzeneMethanol, α-(aMinoMethyl)-α-(4-chlorophenyl)-4-(1H-pyrazol-4-yl)-
CAS No.:857532-13-9
Molecular Formula:C17H16ClN3O
Molecular Weight:313.787
Hs Code.:
Mol file:857532-13-9.mol

Synonyms:4-bromophenacylamine;2-amino-1-(4-bromo-phenyl)-ethanone;2-Amino-4'-bromoacetophenone;ETH034;2-Amino-1-(4-brom-phenyl)-aethanon;aminomethyl-(4-bromo-phenyl)-ketone;2-amino-1-(4-chloro-phenyl)-1-4-(1H-pyrazol-4-yl)-phenyl-ethanol;2-Amino-4'-bromoacetophenone hydrochloride;

Suppliers and Price of BenzeneMethanol, α-(aMinoMethyl)-α-(4-chlorophenyl)-4-(1H-pyrazol-4-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of BenzeneMethanol, α-(aMinoMethyl)-α-(4-chlorophenyl)-4-(1H-pyrazol-4-yl)-

Chemical Property:

PSA：74.93000
LogP:3.62500

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of BenzeneMethanol, α-(aMinoMethyl)-α-(4-chlorophenyl)-4-(1H-pyrazol-4-yl)-

There total 7 articles about BenzeneMethanol, α-(aMinoMethyl)-α-(4-chlorophenyl)-4-(1H-pyrazol-4-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1056901-64-4
2-(4-chloro-phenyl)-2-hydroxy-2-[4-(1H-pyrazol-4-yl)-phenyl]-ethyl-carbamic acid tert-butyl ester

: 857532-13-9
2-amino-1-(4-chloro-phenyl)-1-[4-(1H-pyrazol-4-yl)-phenyl]-ethanol

Guidance literature:: 2-(4-chloro-phenyl)-2-hydroxy-2-[4-(1H-pyrazol-4-yl)-phenyl]-ethyl-carbamic acid tert-butyl ester; With hydrogenchloride; In methanol; diethyl ether; at 20 ℃; for 20h;

With sodium hydroxide; In water;

Reference yield:

: N-(2-{(4-chloro-phenyl)-[4-(1H-pyrazol-4-yl)-phenyl]-methoxy}-ethyl)-phthalamic acid

: 857532-13-9
2-amino-1-(4-chloro-phenyl)-1-[4-(1H-pyrazol-4-yl)-phenyl]-ethanol

Guidance literature:

Reference yield:

: 857532-00-4
(RS)-2-(4-chloro-phenyl)-2-(4-iodo-phenyl)-oxirane

: 857532-13-9
2-amino-1-(4-chloro-phenyl)-1-[4-(1H-pyrazol-4-yl)-phenyl]-ethanol

Guidance literature:: Multi-step reaction with 4 steps

1: ammonia / methanol / 1 h / 130 °C / Microwave irradiation

2: sodium hydroxide / 1,4-dioxane; water / 24 h / 45 °C

3: potassium phosphate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / methanol; ethanol; water; toluene / 25.5 h / 85 °C

4: hydrogenchloride / methanol; diethyl ether / 20 h / 20 °C

With hydrogenchloride; sodium hydroxide; potassium phosphate; ammonia; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; methanol; diethyl ether; ethanol; water; toluene;