N-(1-benzylpiperidin-4-yl)naphthalene-1-carboxamide

Base Information

Chemical Name:N-(1-benzylpiperidin-4-yl)naphthalene-1-carboxamide
CAS No.:857650-85-2
Molecular Formula:C23H24N2O
Molecular Weight:344.456
Hs Code.:
DSSTox Substance ID:DTXSID60398935
Wikidata:Q82201200
ChEMBL ID:CHEMBL229019

Synonyms:N-(1-benzylpiperidin-4-yl)naphthalene-1-carboxamide;CHEMBL229019;857650-85-2;N-(1-benzylpiperidin-4-yl)-1-naphthamide;SCHEMBL3163809;DTXSID60398935;OTJSLBRSNLJVPH-UHFFFAOYSA-N;BDBM50203375;STK491501;AKOS003376517;CCG-300444;N-(1-benzylpiperidine-4-yl)-1-naphthamide;N-(1-BENZYL-4-PIPERIDINYL)-1-NAPHTHAMIDE;n-(1-benzylpiperidin-4-yl)napth-1-yl carboxamide

Suppliers and Price of N-(1-benzylpiperidin-4-yl)naphthalene-1-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-(1-benzylpiperidin-4-yl)naphthalene-1-carboxamide

Chemical Property:

XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:344.188863393
Heavy Atom Count:26
Complexity:451

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1NC(=O)C2=CC=CC3=CC=CC=C32)CC4=CC=CC=C4

Technology Process of N-(1-benzylpiperidin-4-yl)naphthalene-1-carboxamide

There total 2 articles about N-(1-benzylpiperidin-4-yl)naphthalene-1-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 50541-93-0
4-amino-1-benzylpiperidine

: 86-84-0
1-Naphthyl isocyanate

: 857650-85-2
1-(1-naphthyl)-3-(1-benzylpiperidin-4-yl)urea

Guidance literature:: With dibutyltin diacetate; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/jm010384j

Reference yield:

: 50541-93-0
4-amino-1-benzylpiperidine

: 879-18-5
naphthalene-1-carbonic acid chloride

: 857650-85-2
1-(1-naphthyl)-3-(1-benzylpiperidin-4-yl)urea

Guidance literature:: With triethylamine; In ethyl acetate; at 20 ℃;
DOI:10.1016/j.bmcl.2006.12.096

Reference yield:

: 857650-85-2
1-(1-naphthyl)-3-(1-benzylpiperidin-4-yl)urea

: naphthalene-1-carboxylic acid [1-(1-phenyl-ethyl)-piperidin-4-yl]-amide

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium formate / Pd/C / methanol / Heating

2: K₂CO₃ / dimethylformamide / Heating

With ammonium formate; potassium carbonate; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2006.12.096