L-Phenylalanine, N-(2,6-dichlorobenzoyl)-4-nitro-, 1-methylethyl ester

Base Information

Chemical Name:L-Phenylalanine, N-(2,6-dichlorobenzoyl)-4-nitro-, 1-methylethyl ester
CAS No.:857870-36-1
Molecular Formula:C19H18Cl2N2O5
Molecular Weight:425.268
Hs Code.:

Synonyms:

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Chemical Property of L-Phenylalanine, N-(2,6-dichlorobenzoyl)-4-nitro-, 1-methylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

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Technology Process of L-Phenylalanine, N-(2,6-dichlorobenzoyl)-4-nitro-, 1-methylethyl ester

There total 1 articles about L-Phenylalanine, N-(2,6-dichlorobenzoyl)-4-nitro-, 1-methylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 401906-14-7
Nα-(2,6-dichlorobenzoyl)-4-nitro-L-phenylalanine

: 67-63-0,8013-70-5
isopropyl alcohol

: 857870-36-1
Nα-(2,6-dichlorobenzoyl)-4-nitro-L-phenylalanine isopropyl ester

Guidance literature:: With methanesulfonic acid; at 60 - 65 ℃; for 16 - 19h; Product distribution / selectivity;

Reference yield:

: 857870-36-1
Nα-(2,6-dichlorobenzoyl)-4-nitro-L-phenylalanine isopropyl ester

: 857870-47-4
4-amino-Nα-(2,6-dichlorobenzoyl)-L-phenylalanine isopropyl ester

Guidance literature:: With hydrogen; 3percent Pt-S/C; In tetrahydrofuran; isopropyl alcohol; at 20 ℃; under 760.051 Torr;

Reference yield:

: 857870-36-1
Nα-(2,6-dichlorobenzoyl)-4-nitro-L-phenylalanine isopropyl ester

: N-(2,6-dichlorobenzoyl)-4-(6-(hydroxymethyl)-1-methyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-3-(2H)-yl)-L-phenylalanine isopropylester

Guidance literature:: Multi-step reaction with 6 steps

1.1: hydrogen / 3percent Pt-S/C / tetrahydrofuran; isopropyl alcohol / 20 °C

2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / water; N,N-dimethyl-formamide / 16 h / 0 - 20 °C

3.1: N,N-dimethyl-formamide / 20 - 80 °C

4.1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C

5.1: triethylamine / palladium diacetate / water; N,N-dimethyl-formamide / 11 h / 70 °C

6.1: chloroformic acid ethyl ester; triethylamine / tetrahydrofuran / 0.5 h / 0 °C

6.2: 1 h / 0 °C

With hydrogen; chloroformic acid ethyl ester; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; palladium diacetate; In tetrahydrofuran; water; N,N-dimethyl-formamide; isopropyl alcohol;