Lithium diethylamide

Base Information

• Chemical Name: Lithium diethylamide
• CAS No.: 816-43-3
• Molecular Formula: C4H10LiN
• Molecular Weight: 80.079
• European Community (EC) Number: 212-433-4
• DSSTox Substance ID: DTXSID001002077
• Nikkaji Number: J350.600B
• Mol file: 816-43-3.mol

Synonyms:Lithium diethylamide;816-43-3;lithium;diethylazanide;EINECS 212-433-4;LITHIUM DIETHYL AMIDE;Diethylaminolithium;LiNEt2;MFCD00040489;Lithium N-ethylethanaminide;C4H11N.Li;C4-H11-N.Li;Lithium diethylamide, >=95%;AHNJTQYTRPXLLG-UHFFFAOYSA-N;DTXSID001002077;Ethanamine, N-ethyl-, lithium salt

Chemical Property of Lithium diethylamide

Chemical Property:

• PSA: 3.24000
• LogP: 0.79250
• Sensitive.: moisture sensitive
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 79.09732776
• Heavy Atom Count: 6
• Complexity: 15

Purity/Quality:

98%Min ^*data from raw suppliers

Lithium diethylamide, 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): FC
• Hazard Codes: F,C
• Statements: 17-34
• Safety Statements: 16-26-27-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Organic Compounds, Metal Salts
• Canonical SMILES: [Li+].CC[N-]CC

Technology Process of Lithium diethylamide

There total 10 articles about Lithium diethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

diethylamine (109-89-7) → lithium diethylamide (816-43-3)

Guidance literature:

With n-butyllithium; In hexane; at 0 - 20 ℃; for 1h; Inert atmosphere; Schlenk technique;

DOI:10.1039/c6ra18367k

Reference yield:

diisopropylamine (108-18-9) → lithium diethylamide (816-43-3)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexanes; at 0 ℃;

Reference yield:

n-butyllithium (109-72-8,29786-93-4) + diethylamine (109-89-7) → lithium diethylamide (816-43-3)

Guidance literature:

In hexane;

DOI:10.1021/ol007060u

upstream raw materials:

diphenylmethyllithium

diethylamine

trityllithium

n-butyllithium

Downstream raw materials:

2-(diethylamine)ethanethiol

N,N-diethyl-4-methoxyaniline

N,N-diethyl-3-methoxyaniline

2-Diaethylamino-1,1-diphenyl-aethanol-(1)

Refernces

• 1、 Han, Hong-Fei,Guo, Zhi-Qiang,Zhang, Shao-Feng,Li, Jie,Wei, Xue-Hong. "Guanidinatoaluminum complexes: Synthesis, crystal structures and reactivities". . p. 101437 - 101446. Retrieved 2016.
• 2、 -. "IMIDE COMPLEX, METHOD FOR PRODUCING THE SAME, METAL-CONTAINING THIN FILM AND METHOD FOR PRODUCING THE SAME". Page/Page column 26. . Retrieved 2009/06/27.