Propanamide, N-phenyl-N-[(3R,4R)-1-(2-phenylethyl)-3-propyl-4-piperidinyl]-, rel-

Base Information

Chemical Name:Propanamide, N-phenyl-N-[(3R,4R)-1-(2-phenylethyl)-3-propyl-4-piperidinyl]-, rel-
CAS No.:86151-75-9
Molecular Formula:C₂₅H₃₄N₂O
Molecular Weight:378.558
Hs Code.:

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Propanamide, N-phenyl-N-[(3R,4R)-1-(2-phenylethyl)-3-propyl-4-piperidinyl]-, rel-

Chemical Property:

Purity/Quality:

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Technology Process of Propanamide, N-phenyl-N-[(3R,4R)-1-(2-phenylethyl)-3-propyl-4-piperidinyl]-, rel-

There total 16 articles about Propanamide, N-phenyl-N-[(3R,4R)-1-(2-phenylethyl)-3-propyl-4-piperidinyl]-, rel- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 86151-89-5
3-allyl-1-carbethoxy-4-piperidone

: 86151-75-9,86151-76-0,88371-69-1
trans 1-phenethyl-3-propyl-4-(N-phenylpropionamido)piperidine

Guidance literature:: Multi-step reaction with 6 steps

1: 26.5 g / p-toluenesulphonic acid monohydrate / toluene / 18 h / Heating

2: 22.2 g / NaBH₄ / ethanol

3: H₂/Raney nickel / ethanol / 2280 Torr / Ambient temperature

4: KOH / propan-2-ol / Heating

5: Na₂CO₃, KI / acetonitrile / Heating

With potassium hydroxide; sodium tetrahydroborate; hydrogen; nickel; sodium carbonate; toluene-4-sulfonic acid; potassium iodide; In ethanol; isopropyl alcohol; toluene; acetonitrile;

Reference yield:

: 86151-94-2
3-Allyl-4-[(E)-phenylimino]-piperidine-1-carboxylic acid ethyl ester

: 86151-75-9,86151-76-0,88371-69-1
trans 1-phenethyl-3-propyl-4-(N-phenylpropionamido)piperidine

Guidance literature:: Multi-step reaction with 5 steps

1: 22.2 g / NaBH₄ / ethanol

2: H₂/Raney nickel / ethanol / 2280 Torr / Ambient temperature

3: KOH / propan-2-ol / Heating

4: Na₂CO₃, KI / acetonitrile / Heating

With potassium hydroxide; sodium tetrahydroborate; hydrogen; nickel; sodium carbonate; potassium iodide; In ethanol; isopropyl alcohol; acetonitrile;

Reference yield:

: 86151-90-8
3-Allyl-4-phenylamino-piperidine-1-carboxylic acid ethyl ester

: 86151-75-9,86151-76-0,88371-69-1
trans 1-phenethyl-3-propyl-4-(N-phenylpropionamido)piperidine

Guidance literature:: Multi-step reaction with 4 steps

1: H₂/Raney nickel / ethanol / 2280 Torr / Ambient temperature

2: KOH / propan-2-ol / Heating

3: Na₂CO₃, KI / acetonitrile / Heating

With potassium hydroxide; hydrogen; nickel; sodium carbonate; potassium iodide; In ethanol; isopropyl alcohol; acetonitrile;