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Propionic anhydride

Base Information Edit
  • Chemical Name:Propionic anhydride
  • CAS No.:123-62-6
  • Molecular Formula:C6H10O3
  • Molecular Weight:130.144
  • Hs Code.:2915 90 70
  • European Community (EC) Number:204-638-2
  • ICSC Number:0558
  • UN Number:2496
  • UNII:E3A2VV18E6
  • DSSTox Substance ID:DTXSID1027007
  • Nikkaji Number:J5.542E
  • Wikipedia:Propionic_anhydride
  • Wikidata:Q418066
  • Metabolomics Workbench ID:130657
  • ChEMBL ID:CHEMBL3186472
  • Mol file:123-62-6.mol
Propionic anhydride

Synonyms:propanoic anhydride;propionic anhydride

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Chemical Property of Propionic anhydride Edit
Chemical Property:
  • Appearance/Colour:colourless liquid with an unpleasant odour 
  • Vapor Pressure:10 mm Hg ( 57.7 °C) 
  • Melting Point:-42 ºC 
  • Refractive Index:n20/D 1.404(lit.)  
  • Boiling Point:168.4 ºC at 760 mmHg 
  • Flash Point:73.9 ºC 
  • PSA:43.37000 
  • Density:1.015 g/cm3 
  • LogP:0.87620 
  • Storage Temp.:Store below +30°C. 
  • Sensitive.:Moisture Sensitive 
  • Solubility.:H2O: decomposes (when in contact with water) 
  • Water Solubility.:hydrolyses 
  • XLogP3:0.8
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:4
  • Exact Mass:130.062994177
  • Heavy Atom Count:9
  • Complexity:104
  • Transport DOT Label:Corrosive
Purity/Quality:
Safty Information:
  • Pictogram(s): Corrosive
  • Hazard Codes:
  • Statements: 34-R34 
  • Safety Statements: 26-45-S45-S26 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Chemical Classes:Other Classes -> Acid Anhydrides, Other
  • Canonical SMILES:CCC(=O)OC(=O)CC
  • Inhalation Risk:No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.
  • Effects of Short Term Exposure:The substance is corrosive to the eyes, skin and respiratory tract. Inhalation of the vapour or aerosol may cause lung oedema. Corrosive on ingestion. The effects may be delayed. Medical observation is indicated.
  • Uses Propionic anhydride is used as a esterifying agent for certain perfume oils, fats, oils, and especially cellulose and as a reagent in organic synthesis. In the production of alkyd resins, dyestuffs and drugs. Has been used as a dehydrating agent in some sulfonations and nitrations.
Technology Process of Propionic anhydride

There total 60 articles about Propionic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With thionyl chloride; In dichloromethane; at 22 - 25 ℃; for 0.0833333h;
DOI:10.1016/S0040-4039(00)85101-1
Guidance literature:
With air; supported Pd/ZrO2 catalyst; at 120 ℃; under 760.051 Torr;
Guidance literature:
With propionyl chloride; In chloroform; Heating;
Refernces Edit