7-Hydroxy-6-methoxy-4-methyl-2H-chromen-2-one

Base Information

Chemical Name:7-Hydroxy-6-methoxy-4-methyl-2H-chromen-2-one
CAS No.:3374-03-6
Molecular Formula:C11H10O4
Molecular Weight:206.198
Hs Code.:
NSC Number:106082
UNII:5SD81O6IC7
DSSTox Substance ID:DTXSID10187417
Nikkaji Number:J101.707A
Wikidata:Q83059122
Mol file:3374-03-6.mol

Synonyms:3374-03-6;7-Hydroxy-6-methoxy-4-methyl-2H-chromen-2-one;5SD81O6IC7;Coumarin, 7-hydroxy-6-methoxy-4-methyl-;2H-1-Benzopyran-2-one, 7-hydroxy-6-methoxy-4-methyl-;NSC106082;UNII-5SD81O6IC7;7-hydroxy-6-methoxy-4-methyl-chromen-2-one;7-hydroxy-6-methoxy-4-methylcoumarin;7-Hydroxy-6-methoxy-4-methyl-2H-1-benzopyran-2-one;NSC 106082;NSC-106082;7-hydroxy-6-methoxy-4-methylchromen-2-one;SCHEMBL2183416;DTXSID10187417;UMBELLIFERONE, 6-METHOXY-4-METHYL-;7-Hydroxy-6-methoxy-4-methyl-2H-chromen-2-one #

Suppliers and Price of 7-Hydroxy-6-methoxy-4-methyl-2H-chromen-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 7-Hydroxy-6-methoxy-4-methyl-2H-chromen-2-one

Chemical Property:

Vapor Pressure:2.37E-07mmHg at 25°C
Boiling Point:411.3°Cat760mmHg
Flash Point:167.1°C
PSA：59.67000
Density:1.309g/cm³
LogP:1.81560
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:206.05790880
Heavy Atom Count:15
Complexity:297

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=O)OC2=CC(=C(C=C12)OC)O

Technology Process of 7-Hydroxy-6-methoxy-4-methyl-2H-chromen-2-one

There total 3 articles about 7-Hydroxy-6-methoxy-4-methyl-2H-chromen-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 6100-60-3
4-methoxybenzene-1,3-diol

: 141-97-9
ethyl acetoacetate

: 3374-03-6
7-hydroxy-6-methoxy-4-methylchromen-2-one

Guidance literature:: With hydrotacitile; In neat (no solvent); at 70 ℃; for 0.5h; Reagent/catalyst; Green chemistry;
DOI:10.1016/j.molcata.2014.07.024

Reference yield: 48.0%

: 529-84-0
6,7-dihydroxy-4-methylcoumarin

: 74-88-4
methyl iodide

: 4281-40-7
6,7-dimethoxy-4-methylcoumarin

: 3374-03-6
7-hydroxy-6-methoxy-4-methylchromen-2-one

Guidance literature:: With sodium hydride; In dimethyl sulfoxide; at 25 ℃; for 17h; Yields of byproduct given; NaH : pyrocatechlol 3.0;
DOI:10.1039/c39830000400