N-ETHYL-M-CHLOROBENZYLAMINE

Base Information

• Chemical Name: N-ETHYL-M-CHLOROBENZYLAMINE
• CAS No.: 39180-82-0
• Molecular Formula: C9H12 Cl N
• Molecular Weight: 169.654
• Hs Code.: 2921499090
• Mol file: 39180-82-0.mol

Synonyms:m-Chloro-N-ethylbenzylamine

Chemical Property of N-ETHYL-M-CHLOROBENZYLAMINE

Chemical Property:

• Vapor Pressure: 0.0808mmHg at 25°C
• Boiling Point: 226.7°Cat760mmHg
• Flash Point: 90.9°C
• PSA: 12.03000
• Density: 1.063g/cm³
• LogP: 2.84040
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

98.5% ^*data from raw suppliers

[(3-chlorophenyl)methyl](ethyl)amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-ETHYL-M-CHLOROBENZYLAMINE

There total 3 articles about N-ETHYL-M-CHLOROBENZYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3-chloro-N-ethylbenzamide (26819-09-0) → (3-Chloro-benzyl)-ethyl-amine (39180-82-0)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 0.5h; Ambient temperature;

DOI:10.1248/cpb.39.3225

Reference yield:

[1-(3-Chloro-phenyl)-meth-(E)-ylidene]-ethyl-amine (82605-83-2) → (3-Chloro-benzyl)-ethyl-amine (39180-82-0)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2h; Heating;

DOI:10.1021/jm00375a005

Reference yield:

m-Chlorobenzaldehyde (587-04-2) → (3-Chloro-benzyl)-ethyl-amine (39180-82-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1 h / Ambient temperature

2: LiAlH₄ / diethyl ether / 2 h / Heating

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/jm00375a005

upstream raw materials:

3-chloro-N-ethylbenzamide

[1-(3-Chloro-phenyl)-meth-(E)-ylidene]-ethyl-amine

m-Chlorobenzaldehyde

Refernces

• 1、 Ishihara,Kato,Goto. "Central cholinergic agents. I. Potent acetylcholinesterase inhibitors, 2-[ω-[N-alkyl-N-(ω-phenylalkyl)amino]alkyl]-1H-isoindole-1,3(2H)-dion es, based on a new hypothesis of the enzyme's active site". . p. 3225 - 3235. Retrieved 2007/10/02.