1-DANSYLPIPERAZINE

Base Information

Chemical Name:1-DANSYLPIPERAZINE
CAS No.:86516-36-1
Molecular Formula:C16H21N3O2S
Molecular Weight:319.428
Hs Code.:2935009090
European Community (EC) Number:635-524-4
DSSTox Substance ID:DTXSID40471518
Nikkaji Number:J1.177.826G
Wikidata:Q82300038
Mol file:86516-36-1.mol

Synonyms:N,N-dimethyl-5-piperazin-1-ylsulfonylnaphthalen-1-amine;

Suppliers and Price of 1-DANSYLPIPERAZINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Ambeed
N,N-Dimethyl-5-(piperazin-1-ylsulfonyl)naphthalen-1-amine 97%
1g
$ 105.00

Ambeed
N,N-Dimethyl-5-(piperazin-1-ylsulfonyl)naphthalen-1-amine 97%
250mg
$ 44.00

Ambeed
N,N-Dimethyl-5-(piperazin-1-ylsulfonyl)naphthalen-1-amine 97%
100mg
$ 28.00

Total 8 raw suppliers

Chemical Property of 1-DANSYLPIPERAZINE

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:130-135oC
Boiling Point:490.727oC at 760 mmHg
PKA:7.73±0.10(Predicted)
Flash Point:250.583oC
PSA：61.03000
Density:1.263g/cm3
LogP:2.84720
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:319.13544809
Heavy Atom Count:22
Complexity:468

Purity/Quality:

98%Min ^*data from raw suppliers

N,N-Dimethyl-5-(piperazin-1-ylsulfonyl)naphthalen-1-amine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)N3CCNCC3
General Description 1-DANSYLPIPERAZINE (also known as N,N-dimethyl-5-piperazin-1-ylsulfonylnaphthalen-1-amine) is a monosubstituted derivative formed from the reaction of piperazine with dansyl chloride, commonly used as a fluorescent marker or intermediate in analytical chemistry, particularly in precolumn derivatization for detecting piperazine residues in biological samples. It exhibits fluorescence properties suitable for HPLC-FLD detection, demonstrating good linearity, sensitivity, and recovery rates in analytical applications.

Technology Process of 1-DANSYLPIPERAZINE

There total 5 articles about 1-DANSYLPIPERAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 110-85-0
piperazine

: 605-65-2
5-(dimethylamino)naphth-1-ylsulfonyl chloride

: 86516-36-1
dimethyl-[5-(piperazine-1-sulfonyl)-naphthalen-1-yl]-amine

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere; Schlenk technique;
DOI:10.1039/c5ob01305d

Reference yield:

: C₂₁H₂₉N₃O₄S

: 86516-36-1
dimethyl-[5-(piperazine-1-sulfonyl)-naphthalen-1-yl]-amine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; water; at 20 ℃; for 0.666667h;
DOI:10.1016/j.tet.2017.10.020

Reference yield:

: 605-65-2
5-(dimethylamino)naphth-1-ylsulfonyl chloride

: 86516-36-1
dimethyl-[5-(piperazine-1-sulfonyl)-naphthalen-1-yl]-amine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; dimethylaminopyridine / CH₂Cl₂ / 0 - 20 °C

2: 1.56 g / HCO₂H / Pd/C / ethanol / 1 h / Heating

With pyridine; dmap; formic acid; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1021/ja034161p