4,6-Dichloro-2[[(4-methoxyphenyl)methyl]thio]pyrimidine

Base Information

Chemical Name:4,6-Dichloro-2[[(4-methoxyphenyl)methyl]thio]pyrimidine
CAS No.:86627-07-8
Molecular Formula:C12H10Cl2N2OS
Molecular Weight:301.196
Hs Code.:2933599090
DSSTox Substance ID:DTXSID10540043
Wikidata:Q82415908
Mol file:86627-07-8.mol

Synonyms:86627-07-8;4,6-dichloro-2[[(4-methoxyphenyl)methyl]thio]pyrimidine;SCHEMBL99151;DTXSID10540043;ICXWJSQZOOPTJH-UHFFFAOYSA-N;2-p-methoxybenzylthio-4,6-dichloro-pyrimidine;4,6-dichloro-2-(4-methoxybenzylsulfanyl)pyrimidine;4,6-dichloro-2-(4-methoxy-benzylsulfanyl)-pyrimidine;4,6-Dichloro-2-{[(4-methoxyphenyl)methyl]sulfanyl}pyrimidine

Suppliers and Price of 4,6-Dichloro-2[[(4-methoxyphenyl)methyl]thio]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4,6-DICHLORO-2[[(4-METHOXYPHENYL)METHYL]THIO]PYRIMIDINE 95.00%
5MG
$ 505.73

Total 5 raw suppliers

Chemical Property of 4,6-Dichloro-2[[(4-methoxyphenyl)methyl]thio]pyrimidine

Chemical Property:

PSA：60.31000
LogP:4.08430
XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:299.9890895
Heavy Atom Count:18
Complexity:242

Purity/Quality:

97% ^*data from raw suppliers

4,6-DICHLORO-2[[(4-METHOXYPHENYL)METHYL]THIO]PYRIMIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CSC2=NC(=CC(=N2)Cl)Cl

Technology Process of 4,6-Dichloro-2[[(4-methoxyphenyl)methyl]thio]pyrimidine

There total 4 articles about 4,6-Dichloro-2[[(4-methoxyphenyl)methyl]thio]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 86627-06-7
2-<(4-methoxybenzyl)thio>-4,6(1H,5H)-pyrimidinedione

: 86627-07-8
4,6-dichloro-2-(4-methoxyphenylmethylthio)-pyrimidine

Guidance literature:: With α-picoline; trichlorophosphate; for 8h; Heating;
DOI:10.1021/jm9800806

Reference yield:

: 824-94-2
p-methoxybenzyl chloride

: 86627-07-8
4,6-dichloro-2-(4-methoxyphenylmethylthio)-pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 55 percent / NaOH / ethanol; H₂O / 1 h / 60 °C

2: 61.5 percent / POCl₃, N,N-diethylaniline / 8 h / Heating

With sodium hydroxide; N,N-diethylaniline; trichlorophosphate; In ethanol; water;
DOI:10.1021/jm00378a016

Reference yield:

: 824-94-2
p-methoxybenzyl chloride

: 86627-07-8
4,6-dichloro-2-(4-methoxyphenylmethylthio)-pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / aq. NaOH / aq. ethanol / 1.5 h / 60 °C

2: 64 percent / POCl₃, 2-picoline / 8 h / Heating

With α-picoline; sodium hydroxide; trichlorophosphate; In ethanol;
DOI:10.1021/jm9800806