22-Hydroxytetracosanoic acid

Base Information

• Chemical Name: 22-Hydroxytetracosanoic acid
• CAS No.: 18060-70-3
• Molecular Formula: C₂₄H₄₈O₃
• Molecular Weight: 384.643
• NSC Number: 115908
• DSSTox Substance ID: DTXSID00297418
• Nikkaji Number: J297.239E
• Mol file: 18060-70-3.mol

Synonyms:22-hydroxytetracosanoic acid;18060-70-3;22-hydroxytetraco-sanoic acid;DTXSID00297418;NSC115908;NSC-115908

Chemical Property of 22-Hydroxytetracosanoic acid

Chemical Property:

• Vapor Pressure: 1.27E-12mmHg at 25°C
• Boiling Point: 511.9°Cat760mmHg
• Flash Point: 277.5°C
• Density: 0.921g/cm³
• XLogP3: 9.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 22
• Exact Mass: 384.36034539
• Heavy Atom Count: 27
• Complexity: 304

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(CCCCCCCCCCCCCCCCCCCCC(=O)O)O

Technology Process of 22-Hydroxytetracosanoic acid

There total 4 articles about 22-Hydroxytetracosanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

docosanedioic acid (505-56-6) → 22-hydroxy-tetracosanoic acid (18060-70-3)

Guidance literature:

Multi-step reaction with 4 steps

1: H₂SO₄ / beim Verestern

2: KOH; methanol; benzene

3: SOCl₂ / Unsetzung des Saeurechlorids mit C₂H₅ZnI in Toluol und Hydrierung des entstandenen Oxocarbonsaeureesters an Kupferchromit in Methanol bei 150grad und 200 at

With methanol; potassium hydroxide; thionyl chloride; sulfuric acid; benzene;

Reference yield:

1,20-eicosanedicarboxylic acid monomethyl ester (7511-30-0) → 22-hydroxy-tetracosanoic acid (18060-70-3)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / Unsetzung des Saeurechlorids mit C₂H₅ZnI in Toluol und Hydrierung des entstandenen Oxocarbonsaeureesters an Kupferchromit in Methanol bei 150grad und 200 at

With thionyl chloride;

Reference yield:

docosanedioic acid dimethyl ester (22399-98-0) → 22-hydroxy-tetracosanoic acid (18060-70-3)

Guidance literature:

Multi-step reaction with 3 steps

1: KOH; methanol; benzene

2: SOCl₂ / Unsetzung des Saeurechlorids mit C₂H₅ZnI in Toluol und Hydrierung des entstandenen Oxocarbonsaeureesters an Kupferchromit in Methanol bei 150grad und 200 at

With methanol; potassium hydroxide; thionyl chloride; benzene;

upstream raw materials:

22-hydroxy-tetracosanoic acid methyl ester

docosanedioic acid

1,20-eicosanedicarboxylic acid monomethyl ester

docosanedioic acid dimethyl ester