N-{4-[(Benzenesulfonyl)amino]-3-chlorophenyl}-2-bromoacetamide

Base Information

Chemical Name:N-{4-[(Benzenesulfonyl)amino]-3-chlorophenyl}-2-bromoacetamide
CAS No.:86785-43-5
Molecular Formula:C14H12BrClN2O3S
Molecular Weight:403.67900
Hs Code.:
DSSTox Substance ID:DTXSID60522213
Wikidata:Q82387290

Synonyms:86785-43-5;DTXSID60522213;N-{4-[(Benzenesulfonyl)amino]-3-chlorophenyl}-2-bromoacetamide

Suppliers and Price of N-{4-[(Benzenesulfonyl)amino]-3-chlorophenyl}-2-bromoacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of N-{4-[(Benzenesulfonyl)amino]-3-chlorophenyl}-2-bromoacetamide

Chemical Property:

Melting Point:158-160 °C
PSA：87.14000
Density:1.704±0.06 g/cm3(Predicted)
LogP:5.27750
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:401.94405
Heavy Atom Count:22
Complexity:477

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)S(=O)(=O)NC2=C(C=C(C=C2)NC(=O)CBr)Cl

Technology Process of N-{4-[(Benzenesulfonyl)amino]-3-chlorophenyl}-2-bromoacetamide

There total 6 articles about N-{4-[(Benzenesulfonyl)amino]-3-chlorophenyl}-2-bromoacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 86785-28-6
N¹-(phenylsulfonyl)-N⁴-(bromoacetyl)benzoquinone diimine

: 86785-43-5
2'-chloro-4'-(bromoacetamido)benzenesulfonanilide

Guidance literature:: With hydrogenchloride; In acetic acid; for 1h; Ambient temperature;
DOI:10.1021/jo00167a002

Reference yield:

: 1829-81-8
N-(4-nitrophenyl)benzenesulfonamide

: 86785-43-5
2'-chloro-4'-(bromoacetamido)benzenesulfonanilide

Guidance literature:: Multi-step reaction with 4 steps

1: 77 percent / sodium dithionite / methanol; aq. NH₃ / 1.) 30 min, 2.) refrigerator, 1 h

2: 81 percent / potassium bicarbonate / CHCl₃ / 24.5 h / Ambient temperature

3: lead tetraacetate / CHCl₃ / 2 h / Ambient temperature

4: 75 percent / conc. HCl / acetic acid; acetic acid / 1 h / Ambient temperature

With lead(IV) acetate; hydrogenchloride; sodium dithionite; potassium hydrogencarbonate; In methanol; ammonium hydroxide; chloroform; acetic acid;
DOI:10.1021/jo00167a002

Reference yield:

: 5466-91-1
N-phenylsulfonyl-1,4-phenylenediamine

: 86785-43-5
2'-chloro-4'-(bromoacetamido)benzenesulfonanilide

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / potassium bicarbonate / CHCl₃ / 24.5 h / Ambient temperature

2: lead tetraacetate / CHCl₃ / 2 h / Ambient temperature

3: 75 percent / conc. HCl / acetic acid; acetic acid / 1 h / Ambient temperature

With lead(IV) acetate; hydrogenchloride; potassium hydrogencarbonate; In chloroform; acetic acid;
DOI:10.1021/jo00167a002