3-Methyl-2-[(naphthalen-1-yl)methyl]benzoic acid

Base Information

Chemical Name:3-Methyl-2-[(naphthalen-1-yl)methyl]benzoic acid
CAS No.:86802-66-6
Molecular Formula:C19H16O2
Molecular Weight:276.335
Hs Code.:
DSSTox Substance ID:DTXSID20520715
Wikidata:Q82384778

Synonyms:86802-66-6;3-Methyl-2-[(naphthalen-1-yl)methyl]benzoic acid;3-METHYL-2-(NAPHTHALEN-1-YLMETHYL)BENZOIC ACID;DTXSID20520715

Suppliers and Price of 3-Methyl-2-[(naphthalen-1-yl)methyl]benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-Methyl-2-[(naphthalen-1-yl)methyl]benzoic acid

Chemical Property:

XLogP3:5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:276.115029749
Heavy Atom Count:21
Complexity:365

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=CC=C1)C(=O)O)CC2=CC=CC3=CC=CC=C32

Technology Process of 3-Methyl-2-[(naphthalen-1-yl)methyl]benzoic acid

There total 4 articles about 3-Methyl-2-[(naphthalen-1-yl)methyl]benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 86785-13-9
4-methyl-3-(1-naphthylmethyl)phthalide

: 86802-66-6
3-methyl-2-(1-naphthylmethyl)benzoic acid

Guidance literature:: With potassium hydroxide; copper; zinc; In pyridine; water; for 16h; Heating;
DOI:10.1021/jo00167a019

Reference yield:

: 4792-30-7
3-methylphthalic acid anhydride

: 86802-66-6
3-methyl-2-(1-naphthylmethyl)benzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: benzene; diethyl ether / 0.5 h / 40 °C

2: 52.1 g / 80percent H₂SO₄ / H₂O / 0.5 h / 85 - 90 °C

3: 99 percent / 55percent HI, red phosphorus / acetic acid / 5 h / Heating

4: 95 percent / Zn-Cu, 10percent KOH / pyridine; H₂O / 16 h / Heating

With phosphorus; potassium hydroxide; sulfuric acid; hydrogen iodide; copper; zinc; In pyridine; diethyl ether; water; acetic acid; benzene;
DOI:10.1021/jo00167a019

Reference yield:

: 703-55-9
1-naphthylmagnesiumbromide

: 86802-66-6
3-methyl-2-(1-naphthylmethyl)benzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: benzene; diethyl ether / 0.5 h / 40 °C

2: 52.1 g / 80percent H₂SO₄ / H₂O / 0.5 h / 85 - 90 °C

3: 99 percent / 55percent HI, red phosphorus / acetic acid / 5 h / Heating

4: 95 percent / Zn-Cu, 10percent KOH / pyridine; H₂O / 16 h / Heating

With phosphorus; potassium hydroxide; sulfuric acid; hydrogen iodide; copper; zinc; In pyridine; diethyl ether; water; acetic acid; benzene;
DOI:10.1021/jo00167a019