1H-Carbazole, 2,3,4,9-tetrahydro-9-phenyl-

Base Information

• Chemical Name: 1H-Carbazole, 2,3,4,9-tetrahydro-9-phenyl-
• CAS No.: 86844-02-2
• Molecular Formula: C18H17N
• Molecular Weight: 247.34
• Mol file: 86844-02-2.mol

Synonyms:9-phenyl-2,3,4,9-tetrahydro-1H-carbazole;9-phenyl-6,7,8,9-tetrahydro-5H-carbazole;9-Phenyl-1,2,3,4-tetrahydro-carbazol;9-phenyl-1,2,3,4-tetrahydro-9H-carbazole;9-phenyl-1,2,3,4-tetrahydro-carbazole;

Chemical Property of 1H-Carbazole, 2,3,4,9-tetrahydro-9-phenyl-

Chemical Property:

• PSA: 4.93000
• LogP: 4.50930

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Carbazole, 2,3,4,9-tetrahydro-9-phenyl-

There total 12 articles about 1H-Carbazole, 2,3,4,9-tetrahydro-9-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.3%

→ 9-phenyl-6,7,8,9-tetrahydro-5H-carbazole (86844-02-2)

Guidance literature:

With ?di-tert-butyl(2,2-diphenyl-1-methyl-1-cyclopropyl)phosphine; bis(η3-allyl-μ-chloropalladium(II)); methylmagnesium chloride; In tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene; at 5 ℃; Inert atmosphere; Reflux;

Reference yield: 95.0%

1,2,3,4-tetrahydrocarbazole (942-01-8) + iodobenzene (591-50-4) → 9-phenyl-6,7,8,9-tetrahydro-5H-carbazole (86844-02-2)

Guidance literature:

With copper; caesium carbonate; In propyl cyanide; for 10h; Reflux; Inert atmosphere;

DOI:10.1002/adsc.200700535

Reference yield: 83.0%

2-(2-bromophenyl)cyclohexen-1-yl triflate (847355-59-3) + aniline (62-53-3) → 9-phenyl-6,7,8,9-tetrahydro-5H-carbazole (86844-02-2)

Guidance literature:

With caesium carbonate; bis[2-(diphenylphosphino)phenyl] ether; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In toluene; at 100 ℃; for 20h;

DOI:10.1002/anie.200461598

upstream raw materials:

cyclohexanone

N-nitrosodiphenylamine

1,2,3,4-tetrahydrocarbazole

triphenylbismuth bis(trifluoroacetate)

Downstream raw materials:

N-phenylcarbazole

4b-nitro-9-phenyl-4b,5,6,7,8,9-hexahydro-carbazol-8a-ol

9-Phenyl-1-pyrrolidin-1-ylmethyl-2,3,4,9-tetrahydro-1H-carbazole

9-Phenyl-1-piperidin-1-ylmethyl-2,3,4,9-tetrahydro-1H-carbazole