5-Acetamidopyridine-2-carboxylic acid

Base Information

Chemical Name:5-Acetamidopyridine-2-carboxylic acid
CAS No.:86873-62-3
Molecular Formula:C₈H₈N₂O₃
Molecular Weight:180.163
Hs Code.:
European Community (EC) Number:868-493-2
ChEMBL ID:CHEMBL243143
DSSTox Substance ID:DTXSID70415046
Wikidata:Q82224172

Synonyms:5-acetamidopyridine-2-carboxylic acid;86873-62-3;5-acetamidopicolinic acid;2-Pyridinecarboxylic acid, 5-(acetylamino)-;pyridine deriv. 26;BDBM4731;CHEMBL243143;SCHEMBL3621493;DTXSID70415046;5-acetamidopyridine-2-carboxylicacid;AKOS015966519;AS-65690;5-(acetylamino)pyridine-2-carboxylic acid;CS-0094236;EN300-131475;N16822;5-Acetylaminopyridine-2-carboxylic acid, sodium salt

Suppliers and Price of 5-Acetamidopyridine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 5-Acetamidopyridine-2-carboxylic acid

Chemical Property:

XLogP3:-0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:180.05349212
Heavy Atom Count:13
Complexity:217

Purity/Quality:: ≥99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CN=C(C=C1)C(=O)O

Technology Process of 5-Acetamidopyridine-2-carboxylic acid

There total 7 articles about 5-Acetamidopyridine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4214-76-0,67476-67-9
5-nitro-pyridin-2-ylamine

: 86873-62-3
5-Acetylaminopyridin-2-carbonsaeure

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) 48 percent HBr, Br₂; 2.) NaNO₂ / 1) 30-40 deg C; 2) -5 deg C, H₂O; 10-15 Deg C, 90 min.; 3) 40 deg C_. 15 min

2: dimethylsulfoxide / 0.08 h / 180 °C

3: 54 percent / HCl / 1.5 h / Heating

4: 70 percent / H₂S, 25 percent NH₃

5: pyridine / 3 h

With hydrogenchloride; ammonium hydroxide; hydrogen sulfide; hydrogen bromide; bromine; sodium nitrite; In pyridine; dimethyl sulfoxide;

Reference yield:

: 4487-59-6
2-bromo-5-nitropyridine

: 86873-62-3
5-Acetylaminopyridin-2-carbonsaeure

Guidance literature:: Multi-step reaction with 4 steps

1: dimethylsulfoxide / 0.08 h / 180 °C

2: 54 percent / HCl / 1.5 h / Heating

3: 70 percent / H₂S, 25 percent NH₃

4: pyridine / 3 h

With hydrogenchloride; ammonium hydroxide; hydrogen sulfide; In pyridine; dimethyl sulfoxide;

Reference yield:

: 30651-24-2
5-nitropicolinic acid

: 86873-62-3
5-Acetylaminopyridin-2-carbonsaeure

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / H₂S, 25 percent NH₃

2: pyridine / 3 h

With ammonium hydroxide; hydrogen sulfide; In pyridine;