5-phenyl-2-(prop-2-en-1-yl)-2H-tetrazole

Base Information

• Chemical Name: 5-phenyl-2-(prop-2-en-1-yl)-2H-tetrazole
• CAS No.: 65103-37-9
• Molecular Formula: C10H10 N4
• Molecular Weight: 186.216
• Mol file: 65103-37-9.mol

Synonyms:2H-Tetrazole,5-phenyl-2-(2-propenyl)- (9CI); NSC 314079

Chemical Property of 5-phenyl-2-(prop-2-en-1-yl)-2H-tetrazole

Chemical Property:

• Vapor Pressure: 0.00012mmHg at 25°C
• Boiling Point: 335.4°Cat760mmHg
• Flash Point: 156.6°C
• Density: 1.15g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-phenyl-2-(prop-2-en-1-yl)-2H-tetrazole

There total 4 articles about 5-phenyl-2-(prop-2-en-1-yl)-2H-tetrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

5-Phenyl-1H-tetrazole (18039-42-4,3999-10-8) + allyl methyl carbonate (35466-83-2) → 2-allyl-5-phenyl-2H-tetrazole (65103-37-9)

Guidance literature:

With bis(η3-allyl-μ-chloropalladium(II)); potassium carbonate; bis[2-(diphenylphosphino)phenyl] ether; In water; toluene; at 45 ℃; for 19h; Schlenk technique; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.orglett.0c01329

Reference yield: 79.0%

5-Phenyl-1H-tetrazole (18039-42-4,3999-10-8) + allyl bromide (106-95-6) → 1-allyl-5-phenyltetrazole (65103-36-8) + 2-allyl-5-phenyl-2H-tetrazole (65103-37-9)

Guidance literature:

5-Phenyl-1H-tetrazole; With sodium carbonate; In acetone; at 20 ℃; for 0.5h;

allyl bromide; In acetone; for 2h; Reflux;

DOI:10.1021/acs.jpca.7b08078

Reference yield:

benzonitrile (100-47-0) → 2-allyl-5-phenyl-2H-tetrazole (65103-37-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide

2: sodium hydrogencarbonate / ethanol

With sodium azide; sodium hydrogencarbonate; In ethanol;

DOI:10.1134/S0022476615010242

upstream raw materials:

benzonitrile

5-Phenyl-1H-tetrazole

allyl bromide

allyl methyl carbonate

Downstream raw materials:

5-Phenyl-1H-tetrazole