Technology Process of 4H-1,2,4-Triazole,
3-(4-bromophenyl)-5-[4-(1,1-dimethylethyl)phenyl]-4-phenyl-
There total 4 articles about 4H-1,2,4-Triazole,
3-(4-bromophenyl)-5-[4-(1,1-dimethylethyl)phenyl]-4-phenyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 88 percent / hydrazine monohydrate / ethanol / 24 h / Heating
2: 100 percent / sodium carbonate / 1-methyl-pyrrolidin-2-one / 24 h / 20 °C
3: 17 percent / phosphorus trichloride / 1,2-dichloro-benzene / 3 h / Heating
With
sodium carbonate; hydrazine hydrate; phosphorus trichloride;
In
1-methyl-pyrrolidin-2-one; ethanol; 1,2-dichloro-benzene;
DOI:10.1021/ja054777+
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 100 percent / sodium carbonate / 1-methyl-pyrrolidin-2-one / 24 h / 20 °C
2: 17 percent / phosphorus trichloride / 1,2-dichloro-benzene / 3 h / Heating
With
sodium carbonate; phosphorus trichloride;
In
1-methyl-pyrrolidin-2-one; 1,2-dichloro-benzene;
DOI:10.1021/ja054777+
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sulfuric acid
2.1: hydrazine / chloroform / 48 h / 20 °C
3.1: chloroform / 48 h
4.1: phosphorus trichloride / 1,2-dichloro-benzene / 2 h / 100 °C / Inert atmosphere
4.2: 24 h / 180 °C / Inert atmosphere
With
sulfuric acid; hydrazine; phosphorus trichloride;
In
chloroform; 1,2-dichloro-benzene;
