C-(5-bromo-7-chloro-2,3-dihydro-benzofuran-2-yl)-N-BOC-methylamine

Base Information

Chemical Name:C-(5-bromo-7-chloro-2,3-dihydro-benzofuran-2-yl)-N-BOC-methylamine
CAS No.:872518-71-3
Molecular Formula:C14H17BrClNO3
Molecular Weight:362.651
Hs Code.:
Mol file:872518-71-3.mol

Synonyms:C-(5-bromo-7-chloro-2,3-dihydro-benzofuran-2-yl)-N-BOC-methylamine;

Suppliers and Price of C-(5-bromo-7-chloro-2,3-dihydro-benzofuran-2-yl)-N-BOC-methylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
tert-butyl((5-bromo-7-chloro-2,3-dihydrobenzofuran-2-yl)methyl)carbamate
500mg
$ 789.20

AK Scientific
tert-butyl((5-bromo-7-chloro-2,3-dihydrobenzofuran-2-yl)methyl)carbamate
100mg
$ 419.60

Total 5 raw suppliers

Chemical Property of C-(5-bromo-7-chloro-2,3-dihydro-benzofuran-2-yl)-N-BOC-methylamine

Chemical Property:

PSA：47.56000
LogP:4.32160

Purity/Quality:

97% ^*data from raw suppliers

tert-butyl((5-bromo-7-chloro-2,3-dihydrobenzofuran-2-yl)methyl)carbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C-(5-bromo-7-chloro-2,3-dihydro-benzofuran-2-yl)-N-BOC-methylamine

There total 8 articles about C-(5-bromo-7-chloro-2,3-dihydro-benzofuran-2-yl)-N-BOC-methylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 24424-99-5
di-tert-butyl dicarbonate

: (5-bromo-7-chloro-2,3-dihydrobenzofuran-2-yl)methanamine

: 872518-71-3
tert-butyl (5-bromo-7-chloro-2,3-dihydrobenzofuran-2-yl)methylcarbamate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 4h;

Reference yield:

: 872518-67-7
C-(7-chloro-2,3-dihydro-benzofuran-2-yl)-N-BOC-methylamine

: 872518-71-3
tert-butyl (5-bromo-7-chloro-2,3-dihydrobenzofuran-2-yl)methylcarbamate

Guidance literature:: With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield:

: 90725-41-0
4-bromo-2-chloro-6-(prop-2-en-1-yl)phenol

: 872518-71-3
tert-butyl (5-bromo-7-chloro-2,3-dihydrobenzofuran-2-yl)methylcarbamate

Guidance literature:: Multi-step reaction with 5 steps

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 0 - 20 °C

1.2: 4 h / 0 - 20 °C

2.1: triethylamine / dichloromethane / 4 h / 0 - 20 °C

3.1: potassium carbonate; sodium azide / N,N-dimethyl-formamide / 2 h / 80 °C

4.1: hydrogen / methanol / 1 h / 20 °C

5.1: triethylamine / dichloromethane / 4 h / 0 - 20 °C

With sodium azide; hydrogen; potassium carbonate; triethylamine; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane; N,N-dimethyl-formamide;