1H-Indole-3-propanoic acid, 5-chloro-1-(diphenylmethyl)-2-methyl-

Base Information

Chemical Name:1H-Indole-3-propanoic acid, 5-chloro-1-(diphenylmethyl)-2-methyl-
CAS No.:872674-68-5
Molecular Formula:C25H22ClNO2
Molecular Weight:403.908
Hs Code.:
DSSTox Substance ID:DTXSID60469073
Wikidata:Q82296650

Synonyms:872674-68-5;1H-Indole-3-propanoic acid, 5-chloro-1-(diphenylmethyl)-2-methyl-;DTXSID60469073

Suppliers and Price of 1H-Indole-3-propanoic acid, 5-chloro-1-(diphenylmethyl)-2-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1H-Indole-3-propanoic acid, 5-chloro-1-(diphenylmethyl)-2-methyl-

Chemical Property:

XLogP3:6.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:403.1339066
Heavy Atom Count:29
Complexity:525

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C2=C(N1C(C3=CC=CC=C3)C4=CC=CC=C4)C=CC(=C2)Cl)CCC(=O)O

Technology Process of 1H-Indole-3-propanoic acid, 5-chloro-1-(diphenylmethyl)-2-methyl-

There total 3 articles about 1H-Indole-3-propanoic acid, 5-chloro-1-(diphenylmethyl)-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: ethyl 3-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]propanoate

: 872674-68-5
3-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]propanoic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; methanol; at 50 ℃;
DOI:10.1021/jm0507882

Reference yield:

: 117752-80-4
Ethyl 5-chloro-2-methyl-1H-indole-3-propanoate

: 872674-68-5
3-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / dimethylformamide / 0.5 h / 0 °C

1.2: 37 percent / dimethylformamide / 0 - 20 °C

2.1: aq. NaOH / tetrahydrofuran; methanol / 50 °C

With sodium hydroxide; sodium hydride; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm0507882

Reference yield:

: 776-74-9
Bromodiphenylmethane

: 872674-68-5
3-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / dimethylformamide / 0.5 h / 0 °C

1.2: 37 percent / dimethylformamide / 0 - 20 °C

2.1: aq. NaOH / tetrahydrofuran; methanol / 50 °C

With sodium hydroxide; sodium hydride; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm0507882