Benzenebutanoic acid, 4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]ethoxy]-, methyl ester

Base Information

Chemical Name:Benzenebutanoic acid, 4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]ethoxy]-, methyl ester
CAS No.:872674-81-2
Molecular Formula:C35H34ClNO3
Molecular Weight:552.113
Hs Code.:

Synonyms:

Suppliers and Price of Benzenebutanoic acid, 4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]ethoxy]-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzenebutanoic acid, 4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]ethoxy]-, methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzenebutanoic acid, 4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]ethoxy]-, methyl ester

There total 5 articles about Benzenebutanoic acid, 4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]ethoxy]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-[(4-chloro-phenyl)-hydrazono]-pentanoic acid ethyl ester

: 872674-81-2
methyl 4-[4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]ethoxy]phenyl]butanoate

Guidance literature:: Multi-step reaction with 4 steps

1.1: ZnCl₂ / 140 °C

2.1: NaH / dimethylformamide / 0.5 h / 0 °C

2.2: 17 percent / dimethylformamide / 0 - 20 °C

3.1: LiAlH₄ / tetrahydrofuran / 0.5 h / 10 °C

4.1: PPh₃; diisopropyl azodicarboxylate / CH₂Cl₂

With lithium aluminium tetrahydride; di-isopropyl azodicarboxylate; sodium hydride; triphenylphosphine; zinc(II) chloride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; 1.1: Fisher indole synthesis / 4.1: Mitsunobu reaction;
DOI:10.1021/jm0507882

Reference yield:

: 872674-73-2
ethyl [5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]acetate

: 872674-81-2
methyl 4-[4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]ethoxy]phenyl]butanoate

Guidance literature:: Multi-step reaction with 2 steps

1: LiAlH₄ / tetrahydrofuran / 0.5 h / 10 °C

2: PPh₃; diisopropyl azodicarboxylate / CH₂Cl₂

With lithium aluminium tetrahydride; di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; dichloromethane; 2: Mitsunobu reaction;
DOI:10.1021/jm0507882

Reference yield:

: 3446-72-8
5-chloro-2-methyl-1H-indole-3-acetic acid ethyl ester

: 872674-81-2
methyl 4-[4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]ethoxy]phenyl]butanoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaH / dimethylformamide / 0.5 h / 0 °C

1.2: 17 percent / dimethylformamide / 0 - 20 °C

2.1: LiAlH₄ / tetrahydrofuran / 0.5 h / 10 °C

3.1: PPh₃; diisopropyl azodicarboxylate / CH₂Cl₂

With lithium aluminium tetrahydride; di-isopropyl azodicarboxylate; sodium hydride; triphenylphosphine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; 3.1: Mitsunobu reaction;
DOI:10.1021/jm0507882