1-(4-(5-Amino-6-methyl-2-pyridyl)aminobenzyl)-4-benzyl-2,3-dioxopiperazine

Base Information

Chemical Name:1-(4-(5-Amino-6-methyl-2-pyridyl)aminobenzyl)-4-benzyl-2,3-dioxopiperazine
CAS No.:77917-42-1
Molecular Formula:C₂₄H₂₅N₅O₂
Molecular Weight:415.495
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10999118
Nikkaji Number:J117.812A
Wikidata:Q82991966
Mol file:77917-42-1.mol

Synonyms:BRN 5651625;77917-42-1;1-(4-(5-Amino-6-methyl-2-pyridyl)aminobenzyl)-4-benzyl-2,3-dioxopiperazine;2,3-Piperazinedione, 1-(p-((5-amino-6-methyl-2-pyridyl)amino)benzyl)-4-benzyl-;DTXSID10999118;LS-111846;1-({4-[(5-Amino-6-methylpyridin-2-yl)amino]phenyl}methyl)-4-benzylpiperazine-2,3-dione;1-[4-[(5-Amino-6-methyl-2-pyridinyl)amino]benzyl]-4-benzyl-2,3-piperazinedione

Suppliers and Price of 1-(4-(5-Amino-6-methyl-2-pyridyl)aminobenzyl)-4-benzyl-2,3-dioxopiperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,3-PIPERAZINEDIONE, 1-(P-((5-AMINO-6-METHYL-2-PYRIDYL)AMINO)BENZYL)-4-BENZYL- 95.00%
5MG
$ 500.24

Total 3 raw suppliers

Chemical Property of 1-(4-(5-Amino-6-methyl-2-pyridyl)aminobenzyl)-4-benzyl-2,3-dioxopiperazine

Chemical Property:

Vapor Pressure:8.58E-16mmHg at 25°C
Boiling Point:630.2°C at 760 mmHg
Flash Point:334.9°C
PSA：91.56000
Density:1.314g/cm³
LogP:3.61680
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:415.20082506
Heavy Atom Count:31
Complexity:615

Purity/Quality:

99% ^*data from raw suppliers

2,3-PIPERAZINEDIONE, 1-(P-((5-AMINO-6-METHYL-2-PYRIDYL)AMINO)BENZYL)-4-BENZYL- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=N1)NC2=CC=C(C=C2)CN3CCN(C(=O)C3=O)CC4=CC=CC=C4)N

Technology Process of 1-(4-(5-Amino-6-methyl-2-pyridyl)aminobenzyl)-4-benzyl-2,3-dioxopiperazine

There total 3 articles about 1-(4-(5-Amino-6-methyl-2-pyridyl)aminobenzyl)-4-benzyl-2,3-dioxopiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 77917-45-4
1-Benzyl-4-[4-(6-methyl-5-nitro-pyridin-2-ylamino)-benzyl]-piperazine-2,3-dione

: 77917-42-1
1-[4-(5-Amino-6-methyl-pyridin-2-ylamino)-benzyl]-4-benzyl-piperazine-2,3-dione

Guidance literature:: With hydrogenchloride; iron; ice cooling, 15 min, then 1 h, 30 - 40 deg C;
DOI:10.1248/cpb.29.1594

Reference yield:

: 22280-60-0
6-chloro-4-methyl-3-nitropyridine

: 77917-42-1
1-[4-(5-Amino-6-methyl-pyridin-2-ylamino)-benzyl]-4-benzyl-piperazine-2,3-dione

Guidance literature:: Multi-step reaction with 2 steps

2: Fe powder, conc. HCl / ice cooling, 15 min, then 1 h, 30 - 40 deg C

With hydrogenchloride; iron;
DOI:10.1248/cpb.29.1594

Reference yield:

: 77917-04-5
1-(4-aminobenzyl)-4-benzyl-2,3-dioxopiperazine

: 77917-42-1
1-[4-(5-Amino-6-methyl-pyridin-2-ylamino)-benzyl]-4-benzyl-piperazine-2,3-dione

Guidance literature:: Multi-step reaction with 2 steps

2: Fe powder, conc. HCl / ice cooling, 15 min, then 1 h, 30 - 40 deg C

With hydrogenchloride; iron;
DOI:10.1248/cpb.29.1594