4-chloro-1-methyl-3-phenylquinolin-2(1H)-one

Base Information

Chemical Name:4-chloro-1-methyl-3-phenylquinolin-2(1H)-one
CAS No.:56857-90-0
Molecular Formula:C16H12ClNO
Molecular Weight:269.7256
Hs Code.:
DSSTox Substance ID:DTXSID50972283
Wikidata:Q82956017

Synonyms:4-chloro-1-methyl-3-phenylquinolin-2(1H)-one;4-chloro-1-methyl-3-phenylquinolin-2-one;56857-90-0;Oprea1_599142;4-chloro-1-methyl-3-phenyl-1,2-dihydroquinolin-2-one;SCHEMBL17025696;DTXSID50972283;AE-406/41055991

Suppliers and Price of 4-chloro-1-methyl-3-phenylquinolin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-chloro-1-methyl-3-phenylquinolin-2(1H)-one

Chemical Property:

Vapor Pressure:3.84E-06mmHg at 25°C
Boiling Point:385.3°Cat760mmHg
Flash Point:186.8°C
PSA：0.00000
Density:1.31g/cm³
LogP:0.00000
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:269.0607417
Heavy Atom Count:19
Complexity:398

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C2=CC=CC=C2C(=C(C1=O)C3=CC=CC=C3)Cl

Technology Process of 4-chloro-1-methyl-3-phenylquinolin-2(1H)-one

There total 10 articles about 4-chloro-1-methyl-3-phenylquinolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 519-66-4
4-hydroxy-1-methyl-3-phenylquinolin-2-one

: 56857-90-0
4-Chloro-1-methyl-2-oxo-3-phenyl-1,2-dihydroquinoline

Guidance literature:: With trichlorophosphate; for 2h; Heating;
DOI:10.1007/BF00809016

Reference yield: 75.0%

: methyl[2-(phenylethynyl)phenyl]carbamic chloride

: 56857-90-0
4-Chloro-1-methyl-2-oxo-3-phenyl-1,2-dihydroquinoline

: (Z)-3-[chloro(phenyl)methylene]-1-methylindolin-2-one

Guidance literature:: With bis(benzonitrile)palladium(II) dichloride; In toluene; at 20 ℃; for 18h; diastereoselective reaction;
DOI:10.1021/jacs.6b08925