1-Pyrrolidinecarboxylic acid, 3-(benzoyloxy)-2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-4-methyl-, 1,1-dimethylethyl ester, (2S,3R,4R)-

Base Information

Chemical Name:1-Pyrrolidinecarboxylic acid, 3-(benzoyloxy)-2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-4-methyl-, 1,1-dimethylethyl ester, (2S,3R,4R)-
CAS No.:872997-50-7
Molecular Formula:C24H39NO5Si
Molecular Weight:449.663
Hs Code.:

1-Pyrrolidinecarboxylic acid,
3-(benzoyloxy)-2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-4-methyl-,
1,1-dimethylethyl ester, (2S,3R,4R)-

Synonyms:

Suppliers and Price of 1-Pyrrolidinecarboxylic acid, 3-(benzoyloxy)-2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-4-methyl-, 1,1-dimethylethyl ester, (2S,3R,4R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-Pyrrolidinecarboxylic acid, 3-(benzoyloxy)-2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-4-methyl-, 1,1-dimethylethyl ester, (2S,3R,4R)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-Pyrrolidinecarboxylic acid, 3-(benzoyloxy)-2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-4-methyl-, 1,1-dimethylethyl ester, (2S,3R,4R)-

There total 10 articles about 1-Pyrrolidinecarboxylic acid, 3-(benzoyloxy)-2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-4-methyl-, 1,1-dimethylethyl ester, (2S,3R,4R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 872997-49-4
2-(tert-butyl-dimethyl-silanyloxymethyl)-3-hydroxy-4-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester

: 98-88-4
benzoyl chloride

: 872997-50-7
3-benzoyloxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-4-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester

Guidance literature:: With dmap; triethylamine; In dichloromethane; for 5h; Heating;
DOI:10.3987/COM-05-10500

Reference yield:

: 872997-48-3
3-hydroxy-2-hydroxymethyl-4-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester

: 872997-50-7
3-benzoyloxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-4-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / Et₃N; DMAP / CH₂Cl₂ / 3 h / 20 °C

2: 93 percent / Et₃N; DMAP / CH₂Cl₂ / 5 h / Heating

With dmap; triethylamine; In dichloromethane;
DOI:10.3987/COM-05-10500

Reference yield:

: 872997-47-2
2,2,7-trimethyl-tetrahydro-[1,3]dioxino[5,4-b]pyrrole-5-carboxylic acid tert-butyl ester

: 872997-50-7
3-benzoyloxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-4-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / p-TsOH*H₂O / methanol / 2 h / 20 °C

2: 91 percent / Et₃N; DMAP / CH₂Cl₂ / 3 h / 20 °C

3: 93 percent / Et₃N; DMAP / CH₂Cl₂ / 5 h / Heating

With dmap; toluene-4-sulfonic acid; triethylamine; In methanol; dichloromethane;
DOI:10.3987/COM-05-10500