Diethyl 2,3-diazabicyclo[2.2.1]heptane-2,3-dicarboxylate

Base Information

Chemical Name:Diethyl 2,3-diazabicyclo[2.2.1]heptane-2,3-dicarboxylate
CAS No.:18860-71-4
Molecular Formula:C₁₁H₁₈N₂O₄
Molecular Weight:242.275
Hs Code.:
NSC Number:109906
DSSTox Substance ID:DTXSID50296557
Nikkaji Number:J1.767.128F
ChEMBL ID:CHEMBL1902972

Synonyms:Diethyl 2,3-diazabicyclo[2.2.1]heptane-2,3-dicarboxylate;18860-71-4;MLS002704195;NSC109906;SCHEMBL7210321;CHEMBL1902972;DTXSID50296557;NSC-109906;SMR001570901;Diethyl 2,3-diazabicyclo[2.2.1]heptane-2,3-dicarboxylate #;2,3-Diaza-bicyclo[2.2.1]heptane-2,3-dicarboxylic acid, diethyl ester

Suppliers and Price of Diethyl 2,3-diazabicyclo[2.2.1]heptane-2,3-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Diethyl 2,3-diazabicyclo[2.2.1]heptane-2,3-dicarboxylate

Chemical Property:

Vapor Pressure:0.000777mmHg at 25°C
Boiling Point:306.3°Cat760mmHg
Flash Point:139.1°C
Density:1.238g/cm³
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:242.12665706
Heavy Atom Count:17
Complexity:291

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)N1C2CCC(C2)N1C(=O)OCC

Technology Process of Diethyl 2,3-diazabicyclo[2.2.1]heptane-2,3-dicarboxylate

There total 5 articles about Diethyl 2,3-diazabicyclo[2.2.1]heptane-2,3-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 14011-60-0
diethyl 2,3-diazanorbornene-2,3-dicarboxylate

: 18860-71-4
diethyl 2,3-diazabicyclo<2.2.1>heptane-2,3-dicarboxylate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethyl acetate; at 20 ℃; for 48h;
DOI:10.1021/acs.joc.0c00763

Reference yield:

: 18860-71-4
diethyl 2,3-diazabicyclo<2.2.1>heptane-2,3-dicarboxylate

Guidance literature:: With ethanol; palladium; under 760 Torr; Hydrogenation;

Reference yield:

: 542-92-7,25568-84-7,7313-32-8
cyclopenta-1,3-diene

: 1972-28-7,218603-74-8
diethylazodicarboxylate

: 18860-71-4
diethyl 2,3-diazabicyclo<2.2.1>heptane-2,3-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: toluene; diethyl ether / 21.5 h / 20 °C / Reflux

2: palladium 10% on activated carbon; hydrogen / ethyl acetate / 48 h / 20 °C

With palladium 10% on activated carbon; hydrogen; In diethyl ether; ethyl acetate; toluene;
DOI:10.1021/acs.joc.0c00763