3-(3,5-dichlorophenyl)benzoic Acid

Base Information

Chemical Name:3-(3,5-dichlorophenyl)benzoic Acid
CAS No.:380228-57-9
Molecular Formula:C₁₃H₈Cl₂O₂
Molecular Weight:267.111
Hs Code.:
DSSTox Substance ID:DTXSID60374158
Nikkaji Number:J1.655.370K
Wikidata:Q82162659
ChEMBL ID:CHEMBL421459
Mol file:380228-57-9.mol

Synonyms:380228-57-9;3-(3,5-dichlorophenyl)benzoic Acid;3',5'-Dichloro-[1,1'-biphenyl]-3-carboxylic acid;3-BIPHENYL-3',5'-DICHLORO-CARBOXYLIC ACID;3',5'-Dichlorobiphenyl-3-carboxylic acid;CHEMBL421459;3',5'-Dichloro-[1,1'-biphenyl]-3-carboxylicacid;3',5'-Dichloro-biphenyl-3-carboxylic acid;SCHEMBL411719;DTXSID60374158;BDBM50475380;MFCD03426495;AKOS015848944;AS-41731;CS-0171089;4-NITRO[1,1-BIPHENYL]-2-CARBOXYLICACID

Suppliers and Price of 3-(3,5-dichlorophenyl)benzoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(3,5-Dichlorophenyl)benzoicacid
1g
$ 210.00

TRC
3-(3,5-Dichlorophenyl)benzoicacid
100mg
$ 50.00

Crysdot
3',5'-Dichloro-[1,1'-biphenyl]-3-carboxylicacid 95+%
5g
$ 424.00

Crysdot
3',5'-Dichloro-[1,1'-biphenyl]-3-carboxylicacid 95+%
25g
$ 1774.00

Crysdot
3',5'-Dichloro-[1,1'-biphenyl]-3-carboxylicacid 95+%
10g
$ 813.00

American Custom Chemicals Corporation
3',5'-DICHLORO-BIPHENYL-3-CARBOXYLIC ACID 95.00%
500MG
$ 787.08

Alichem
3',5'-Dichloro-[1,1'-biphenyl]-3-carboxylicacid
10g
$ 829.21

Alichem
3',5'-Dichloro-[1,1'-biphenyl]-3-carboxylicacid
5g
$ 658.35

Alichem
3',5'-Dichloro-[1,1'-biphenyl]-3-carboxylicacid
25g
$ 1895.28

AK Scientific
3',5'-Dichloro-[1,1'-biphenyl]-3-carboxylicacid
25g
$ 2560.00

Total 9 raw suppliers

Chemical Property of 3-(3,5-dichlorophenyl)benzoic Acid

Chemical Property:

Boiling Point:448°Cat760mmHg
Flash Point:224.7°C
PSA：37.30000
Density:1.397g/cm³
LogP:4.35860
Storage Temp.:2-8°C
XLogP3:4.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:265.9901349
Heavy Atom Count:17
Complexity:273

Purity/Quality:

97% ^*data from raw suppliers

3-(3,5-Dichlorophenyl)benzoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)C(=O)O)C2=CC(=CC(=C2)Cl)Cl

Technology Process of 3-(3,5-dichlorophenyl)benzoic Acid

There total 4 articles about 3-(3,5-dichlorophenyl)benzoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 4.0%

: 67492-50-6
(3,5-dichlorophenyl)boronic acid

: 618-51-9
3-Iodobenzoic acid

: 380228-57-9
3',5'‐dichloro‐(1,1'‐biphenyl)‐3‐carboxylic acid

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane; water; for 16h; Inert atmosphere;
DOI:10.1021/acsmedchemlett.9b00306

Reference yield:

: 656305-82-7
3',5'-dichloro-biphenyl-3-carbaldehyde

: 380228-57-9
3',5'‐dichloro‐(1,1'‐biphenyl)‐3‐carboxylic acid

Guidance literature:: With potassium permanganate; In acetone; at 20 ℃; for 16h;
DOI:10.1021/jm030347n

Reference yield:

: 3032-81-3
3,5-dichloroiodobenzene

: 380228-57-9
3',5'‐dichloro‐(1,1'‐biphenyl)‐3‐carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Pd(PPh₃)4; aq. Na₂CO₃ / toluene; ethanol / 18 h / Heating

2: aq. KMnO₄ / acetone / 16 h / 20 °C

With potassium permanganate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; acetone; toluene; 1: Suzuki coupling;
DOI:10.1021/jm030347n