4-(4-Ethylpiperazin-1-YL)-3-fluoroaniline

Base Information

Chemical Name:4-(4-Ethylpiperazin-1-YL)-3-fluoroaniline
CAS No.:873537-27-0
Molecular Formula:C12H18FN3
Molecular Weight:223.293
Hs Code.:2933599090
European Community (EC) Number:855-181-6
DSSTox Substance ID:DTXSID10444390
Wikidata:Q82262517
Mol file:873537-27-0.mol

Synonyms:873537-27-0;4-(4-ETHYLPIPERAZIN-1-YL)-3-FLUOROANILINE;4-(4-Ethyl-1-piperazinyl)-3-fluoro-benzenamine;MFCD08699561;4-(4-Ethyl-1-piperazinyl)-3-fluorobenzenamine;starbld0009729;3-fluoro-4-(4-ethylpiperazin-1-yl)aniline;4-(4-ethyl-1-piperazinyl)-3-fluoroaniline;SCHEMBL159281;4-(4-ETHYL-PIPERAZIN-1-YL)-3-FLUORO-PHENYLAMINE;DTXSID10444390;IRLDCHVGDGNGFK-UHFFFAOYSA-N;YJB53727;STL412500;AKOS000318483;CCG-358905;GS-5565;PB32660;SY096839;CS-0051197;FT-0684661;4-(4-ETHYLPIPERAZINO)-3-FLUOROANILINE;EN300-231128;A862665;J-513499;BENZENAMINE, 4-(4-ETHYL-1-PIPERAZINYL)-3-FLUORO-;4-(4-Ethyl-1-piperazinyl)-3-fluoro-benzenamine, AldrichCPR

Suppliers and Price of 4-(4-Ethylpiperazin-1-YL)-3-fluoroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline
250mg
$ 55.00

SynQuest Laboratories
4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline
25 g
$ 560.00

SynQuest Laboratories
4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline
1 g
$ 108.00

SynQuest Laboratories
4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline
5 g
$ 180.00

Matrix Scientific
4-(4-Ethyl-1-piperazinyl)-3-fluoro-benzenamine >95%
1g
$ 215.00

Matrix Scientific
4-(4-Ethyl-1-piperazinyl)-3-fluoro-benzenamine >95%
500mg
$ 152.00

Chemenu
4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine 95+%
25g
$ 385.00

Chemenu
4-(4-ethyl-1-piperazinyl)-3-fluoro-benzenamine 95+%
10g
$ 216.00

American Custom Chemicals Corporation
4-(4-ETHYL-1-PIPERAZINYL)-3-FLUORO-BENZENAMINE 95.00%
5MG
$ 505.71

Alichem
4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline
5g
$ 164.16

Total 19 raw suppliers

Chemical Property of 4-(4-Ethylpiperazin-1-YL)-3-fluoroaniline

Chemical Property:

PSA：32.50000
LogP:2.13390
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:223.14847575
Heavy Atom Count:16
Complexity:216

Purity/Quality:

99%, ^*data from raw suppliers

4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1CCN(CC1)C2=C(C=C(C=C2)N)F

Technology Process of 4-(4-Ethylpiperazin-1-YL)-3-fluoroaniline

There total 4 articles about 4-(4-Ethylpiperazin-1-YL)-3-fluoroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 873537-27-0
4-(4-ethylpiperazin-1-yl)-3-fluoroaniline

Guidance literature:

Reference yield:

: 694501-34-3
1-ethyl-4-(2-fluoro-4-nitro-phenyl)-piperazine

: 873537-27-0
4-(4-ethylpiperazin-1-yl)-3-fluoroaniline

Guidance literature:: With hydrogen; nickel; In methanol; at 20 ℃; for 17h;

Reference yield:

: 369-34-6
3,4-difluoronitrobenzene

: 873537-27-0
4-(4-ethylpiperazin-1-yl)-3-fluoroaniline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / dimethyl sulfoxide / 12 h / 90 °C

2: hydrogen; palladium 10% on activated carbon / ethyl acetate; methanol / 6 h / 5171.62 Torr

With palladium 10% on activated carbon; hydrogen; potassium carbonate; In methanol; dimethyl sulfoxide; ethyl acetate;
DOI:10.1016/j.ejmech.2014.01.024