Carbamic acid, [trans-4-[(chloroacetyl)amino]cyclohexyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, [trans-4-[(chloroacetyl)amino]cyclohexyl]-, 1,1-dimethylethyl ester
CAS No.:873537-67-8
Molecular Formula:C13H23ClN2O3
Molecular Weight:290.78600
Hs Code.:
Mol file:873537-67-8.mol

Synonyms:trans-[4-(2-chloroacetylamino)cyclohexyl]carbamic acid tert-butyl ester;tert-butyl trans-4-[(chloroacetyl)amino]cyclohexylcarbamate;

Suppliers and Price of Carbamic acid, [trans-4-[(chloroacetyl)amino]cyclohexyl]-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl((1r,4r)-4-(2-chloroacetamido)cyclohexyl)carbamate 97%
1g
$ 1378.00

Total 1 raw suppliers

Chemical Property of Carbamic acid, [trans-4-[(chloroacetyl)amino]cyclohexyl]-, 1,1-dimethylethyl ester

Chemical Property:

Melting Point:215 - 217 °C (ethanol)
PSA：67.43000
LogP:2.95910

Purity/Quality:: tert-Butyl((1r,4r)-4-(2-chloroacetamido)cyclohexyl)carbamate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbamic acid, [trans-4-[(chloroacetyl)amino]cyclohexyl]-, 1,1-dimethylethyl ester

There total 4 articles about Carbamic acid, [trans-4-[(chloroacetyl)amino]cyclohexyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 79-04-9
chloroacetyl chloride

: 177906-48-8
trans-N-Boc-1,4-cyclohexanediamine

: 873537-67-8,1353977-11-3
trans-[4-(2-chloroacetylamido)cyclohexyl]carbamic acid tert-butyl ester

Guidance literature:: trans-N-Boc-1,4-cyclohexanediamine; With triethylamine; In tetrahydrofuran; at 20 ℃; for 2h;

chloroacetyl chloride; In tetrahydrofuran; at 20 ℃; for 8h;
DOI:10.1021/jm900431g

Reference yield: 89.0%

: 873537-67-8,1353977-11-3
trans-[4-(2-chloroacetylamido)cyclohexyl]carbamic acid tert-butyl ester

Guidance literature:

Reference yield:

: 2615-25-0
trans-1,4-cyclohexyldiamine

: 873537-67-8,1353977-11-3
trans-[4-(2-chloroacetylamido)cyclohexyl]carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / water; methanol / 1 h / 20 °C

2: triethylamine / tetrahydrofuran / 8 h / 20 °C

With hydrogenchloride; triethylamine; In tetrahydrofuran; methanol; water;