Methyl 2,3-dibromo-3-phenylpropionate

Base Information

• Chemical Name: Methyl 2,3-dibromo-3-phenylpropionate
• CAS No.: 21770-48-9
• Molecular Formula: C₁₀H₁₀Br₂O₂
• Molecular Weight: 321.996
• Hs Code.: 2916399090
• Mol file: 21770-48-9.mol

Synonyms:2,3-dibromo-3-phenyl-propionic acid methyl ester;opt.-inakt. 2,3-Dibrom-3-phenyl-propionsaeure-methylester;methyl cinnamate dibromide;2,3-Dibrom-3-phenyl-propionsaeure-methylester;2,3-dibromo-3-phenyl methyl propanoate;

Chemical Property of Methyl 2,3-dibromo-3-phenylpropionate

Chemical Property:

• Vapor Pressure: 0.00107mmHg at 25°C
• Melting Point: 117 °C
• Boiling Point: 301.2°Cat760mmHg
• Flash Point: 135.9°C
• PSA: 26.30000
• Density: 1.728g/cm³
• LogP: 3.05910

Purity/Quality:

99% ^*data from raw suppliers

METHYL-2,3-DIBROMO-3-PHENYLPROPANOATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 2,3-dibromo-3-phenylpropionate

There total 39 articles about Methyl 2,3-dibromo-3-phenylpropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl cinnamate (103-26-4,1754-62-7) → methyl 2,3-dibromo-3-phenylpropanoate (21770-48-9,52742-03-7,52777-73-8,113569-01-0,113626-43-0)

Guidance literature:

With bromine; In dichloromethane; at 25 ℃; for 24h;

DOI:10.1016/j.bmcl.2018.06.006

Reference yield: 99.0%

methyl cinnamate (103-26-4,1754-62-7) → rac-(R,S)-methyl 2,3-dibromo-3-phenylpropanoate (21770-48-9,52742-03-7,52777-73-8,113569-01-0,113626-43-0)

Guidance literature:

With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; 1-(3,5-bis(trifluoromethyl)phenyl)-3-(2-(dimethylamino)ethyl)thiourea; In dichloromethane; at 22 ℃; for 2h; optical yield given as %de; diastereospecific reaction;

DOI:10.1021/ol300456x

Reference yield: 99.0%

Methyl cinnamate (103-26-4,1754-62-7) → rac-(R,S)-methyl 2,3-dibromo-3-phenylpropanoate (21770-48-9,52742-03-7,52777-73-8,113569-01-0,113626-43-0)

Guidance literature:

With hydrogen bromide; dihydrogen peroxide; In tetrachloromethane; at 20 ℃; for 2h;

DOI:10.1016/S0040-4020(99)00628-6

upstream raw materials:

methyl cinnamate

methanol

2,3-dibromo-3-phenylpropanoic acid

Cinnamic acid

Downstream raw materials:

Methyl cinnamate

3-phenyl-aziridine-2-carboxylic acid amide

methyl cinnamate

phenylpropynoic acid methyl ester