Pagpc

Base Information

Chemical Name:Pagpc
CAS No.:84062-61-3
Molecular Formula:C₂₆H₅₂NO₈P
Molecular Weight:537.675
Hs Code.:
DSSTox Substance ID:DTXSID50232955
Mol file:84062-61-3.mol

Synonyms:1-palmitoyl-2-acetyl-glycerophosphocholine;1-palmitoyl-2-acetyl-GPC;1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine;1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine, (R)-isomer;PA-GPC;PAGPC

Suppliers and Price of Pagpc

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alfa Aesar
1-O-Palmitoyl-2-O-acetyl-sn-glycero-3-phosphocholine, 99%
5mg
$ 332.00

Alfa Aesar
1-O-Palmitoyl-2-O-acetyl-sn-glycero-3-phosphocholine, 99%
1mg
$ 93.50

Total 1 raw suppliers

Chemical Property of Pagpc

Chemical Property:

PSA：121.00000
LogP:6.22060
XLogP3:6.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:26
Exact Mass:537.34305461
Heavy Atom Count:36
Complexity:615

Purity/Quality:

98%Min ^*data from raw suppliers

1-O-Palmitoyl-2-O-acetyl-sn-glycero-3-phosphocholine, 99% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)C
Isomeric SMILES:CCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)C

Technology Process of Pagpc

There total 5 articles about Pagpc which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 17364-16-8,17364-17-9,17364-18-0,14863-27-5
1-palmitoyl-sn-glycero-3-phosphocholine

: 108-24-7
acetic anhydride

: 79512-78-0,115154-33-1,84062-61-3
1-palmitoyl-2-O-acetyl-sn-glycero-3-phosphocholine

Guidance literature:: With dmap; In dichloromethane; at 20 ℃; for 20h;
DOI:10.1007/s11746-008-1280-4

Reference yield:

1-0-triphenylmethyl-2-acetyl-sn-glycero-3-phosphocholine: 1-0-triphenylmethyl-2-acetyl-sn-glycero-3-phosphocholine

: 623-65-4
palmitic anhydride

: 79512-78-0,115154-33-1,84062-61-3
1-palmitoyl-2-O-acetyl-sn-glycero-3-phosphocholine

Guidance literature:

Reference yield:

: 28319-77-9,563-24-6
L-glycero-3-phosphorylcholine

: 79512-78-0,115154-33-1,84062-61-3
1-palmitoyl-2-O-acetyl-sn-glycero-3-phosphocholine

Guidance literature:: Multi-step reaction with 2 steps

1.1: dibutyltin oxide / propan-2-ol / 1 h / Heating

1.2: 80 percent / TEA / propan-2-ol / 0.25 h / 25 °C

2.1: 4-dimethylaminopyridine / CH₂Cl₂ / 20 h / 20 °C

With dmap; di(n-butyl)tin oxide; In dichloromethane; isopropyl alcohol;
DOI:10.1016/j.chemphyslip.2007.03.008