Morpholine, 4-((1,3-diphenyl-5-methyl-1H-pyrazol-4-yl)carbonyl)-

Base Information

• Chemical Name: Morpholine, 4-((1,3-diphenyl-5-methyl-1H-pyrazol-4-yl)carbonyl)-
• CAS No.: 125103-49-3
• Molecular Formula: C₂₁H₂₁N₃O₂
• Molecular Weight: 347.417
• DSSTox Substance ID: DTXSID30154646
• Wikidata: Q83021932
• Mol file: 125103-49-3.mol

Synonyms:BRN 4206380;Morpholine, 4-((1,3-diphenyl-5-methyl-1H-pyrazol-4-yl)carbonyl)-;4-((1,3-Diphenyl-5-methyl-1H-pyrazol-4-yl)carbonyl)morpholine;125103-49-3;DTXSID30154646;LS-92832

Chemical Property of Morpholine, 4-((1,3-diphenyl-5-methyl-1H-pyrazol-4-yl)carbonyl)-

Chemical Property:

• Vapor Pressure: 6.2E-13mmHg at 25°C
• Boiling Point: 568.4°Cat760mmHg
• Flash Point: 297.5°C
• Density: 1.21g/cm³
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 347.16337692
• Heavy Atom Count: 26
• Complexity: 468

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=NN1C2=CC=CC=C2)C3=CC=CC=C3)C(=O)N4CCOCC4

Technology Process of Morpholine, 4-((1,3-diphenyl-5-methyl-1H-pyrazol-4-yl)carbonyl)-

There total 2 articles about Morpholine, 4-((1,3-diphenyl-5-methyl-1H-pyrazol-4-yl)carbonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.8%

morpholine (110-91-8,99108-56-2) + 1,3-diphenyl-5-methylpyrazole-4-carboxylic chloride (857058-17-4) → (5-Methyl-1,3-diphenyl-1H-pyrazol-4-yl)-morpholin-4-yl-methanone (125103-49-3)

Guidance literature:

In 1,2-dichloro-ethane; Ambient temperature;

DOI:10.1007/BF00766389

Reference yield:

5-methyl-1,3-diphenyl-1H-pyrazole-4-carboxylic acid (15409-48-0) → (5-Methyl-1,3-diphenyl-1H-pyrazol-4-yl)-morpholin-4-yl-methanone (125103-49-3)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / 1 h / Heating

2: 67.8 percent / 1,2-dichloro-ethane / Ambient temperature

With thionyl chloride; In 1,2-dichloro-ethane;

DOI:10.1007/BF00766389

upstream raw materials:

morpholine

1,3-diphenyl-5-methylpyrazole-4-carboxylic chloride

5-methyl-1,3-diphenyl-1H-pyrazole-4-carboxylic acid