4-(Diphenylmethyl)-alpha-phenyl-1-piperazinepropanol benzoate (ester)

Base Information

Chemical Name:4-(Diphenylmethyl)-alpha-phenyl-1-piperazinepropanol benzoate (ester)
CAS No.:149848-10-2
Molecular Formula:C₃₃H₃₄N₂O₂
Molecular Weight:490.645
Hs Code.:
DSSTox Substance ID:DTXSID10933779

Synonyms:4-(Diphenylmethyl)-alpha-phenyl-1-piperazinepropanol benzoate (ester);1-Piperazinepropanol, 4-(diphenylmethyl)-alpha-phenyl-, benzoate (ester);149848-10-2;DTXSID10933779;C33H34N2O2;C33-H34-N2-O2;LS-113348;3-[4-(Diphenylmethyl)piperazin-1-yl]-1-phenylpropyl benzoate

Suppliers and Price of 4-(Diphenylmethyl)-alpha-phenyl-1-piperazinepropanol benzoate (ester)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of 4-(Diphenylmethyl)-alpha-phenyl-1-piperazinepropanol benzoate (ester)

Chemical Property:

Vapor Pressure:1.08E-15mmHg at 25°C
Boiling Point:628.1°Cat760mmHg
Flash Point:333.7°C
Density:1.144g/cm³
XLogP3:6.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:10
Exact Mass:490.262028332
Heavy Atom Count:37
Complexity:633

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCC(C2=CC=CC=C2)OC(=O)C3=CC=CC=C3)C(C4=CC=CC=C4)C5=CC=CC=C5

Technology Process of 4-(Diphenylmethyl)-alpha-phenyl-1-piperazinepropanol benzoate (ester)

There total 2 articles about 4-(Diphenylmethyl)-alpha-phenyl-1-piperazinepropanol benzoate (ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 98-88-4
benzoyl chloride

: 41332-13-2
γ-(4-benzhydryl piperazin-1-yl)-α-phenyl propanol

: 149848-10-2
γ-(4-benzhydryl piperazin-1-yl)-α-phenyl propanol benzoate

Guidance literature:: With sodium carbonate; In chloroform; for 3.5h;

Reference yield:

: 1-benzhydryl-4(β-benzoylethyl) piperazine dihydrochloride

: 149848-10-2
γ-(4-benzhydryl piperazin-1-yl)-α-phenyl propanol benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / NaOH; NaBH₄ / ethanol; H₂O / 2 h / Heating

2: 97 percent / sodium carbonate / CHCl₃ / 3.5 h / Heating

With sodium hydroxide; sodium tetrahydroborate; sodium carbonate; In ethanol; chloroform; water;
DOI:10.1211/146080800128735539