4-Difluoromethanesulfonylaniline

Base Information

Chemical Name:4-Difluoromethanesulfonylaniline
CAS No.:24906-77-2
Molecular Formula:C7H7 F2 N O2 S
Molecular Weight:207.201
Hs Code.:2921420090
European Community (EC) Number:865-746-9
DSSTox Substance ID:DTXSID80356517
Wikidata:Q82135890
ChEMBL ID:CHEMBL5020201
Mol file:24906-77-2.mol

Synonyms:24906-77-2;4-difluoromethanesulfonylaniline;4-[(difluoromethyl)sulfonyl]aniline;4-(difluoromethylsulfonyl)aniline;4-((Difluoromethyl)sulfonyl)aniline;4-(Difluoromethyl)sulfonylaniline;p-difluoromethylsulfonylaniline;SCHEMBL2149310;CHEMBL5020201;DTXSID80356517;OHQOPPCSAGDCDO-UHFFFAOYSA-N;HMS1754A05;MFCD00182675;AKOS000270966;AT38850;Benzenamine, 4-[(difluoromethyl)sulfonyl]-;CS-0042305;EN300-08917;4-[(difluoromethyl)sulfonyl]aniline, AldrichCPR;A817537;Z55928990;F8880-6969

Suppliers and Price of 4-Difluoromethanesulfonylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-difluoromethanesulfonylaniline
500mg
$ 310.00

SynQuest Laboratories
4-(Difluoromethyl)sulfonylaniline
1 g
$ 192.00

SynQuest Laboratories
4-(Difluoromethyl)sulfonylaniline
5 g
$ 532.00

Matrix Scientific
4-Difluoromethanesulfonylaniline 95%+
2.500g
$ 557.00

Matrix Scientific
4-Difluoromethanesulfonylaniline 95%+
500mg
$ 170.00

Matrix Scientific
4-Difluoromethanesulfonylaniline 95%+
100mg
$ 71.00

Apolloscientific
4-(Difluoromethyl)sulphonylaniline
1g
$ 174.00

Apolloscientific
4-(Difluoromethyl)sulphonylaniline
5g
$ 482.00

American Custom Chemicals Corporation
4-[(DIFLUOROMETHYL)SULFONYL]ANILINE 95.00%
1G
$ 721.57

American Custom Chemicals Corporation
4-[(DIFLUOROMETHYL)SULFONYL]ANILINE 95.00%
5G
$ 1168.42

Total 13 raw suppliers

Chemical Property of 4-Difluoromethanesulfonylaniline

Chemical Property:

Vapor Pressure:1.28E-05mmHg at 25°C
Melting Point:105-106°C
Boiling Point:368.4°Cat760mmHg
PKA:0?+-.0.10(Predicted)
Flash Point:176.6°C
PSA：68.54000
Density:1.431g/cm³
LogP:2.92710
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:207.01655596
Heavy Atom Count:13
Complexity:252

Purity/Quality:

97% ^*data from raw suppliers

4-difluoromethanesulfonylaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 20/21/22
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1N)S(=O)(=O)C(F)F

Technology Process of 4-Difluoromethanesulfonylaniline

There total 2 articles about 4-Difluoromethanesulfonylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24933-57-1
1-[(difluoromethyl)thio]-4-nitrobenzene

: 24906-77-2
4-((difluoromethyl)sulfonyl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: CrO₃ / acetic acid

2: aq. HCl, SnCl₂

With chromium(VI) oxide; hydrogenchloride; tin(ll) chloride; In acetic acid;

Reference yield:

: 13113-79-6
sodium 4-nitrobenzenethiolate

: 24906-77-2
4-((difluoromethyl)sulfonyl)aniline

Guidance literature:: Multi-step reaction with 3 steps

1: aq. NaOH / dioxane

2: CrO₃ / acetic acid

3: aq. HCl, SnCl₂

With chromium(VI) oxide; hydrogenchloride; sodium hydroxide; tin(ll) chloride; In 1,4-dioxane; acetic acid;