6-methoxy-4-phenyl-1-(2,2,2-trifluoroethyl)-2-(1H)-quinazolinone

Base Information

• Chemical Name: 6-methoxy-4-phenyl-1-(2,2,2-trifluoroethyl)-2-(1H)-quinazolinone
• CAS No.: 49830-89-9
• Molecular Formula: C17H13 F3 N2 O2
• Molecular Weight: 334.29
• Mol file: 49830-89-9.mol

Synonyms:1-(2,2,2-Trifluoroethyl)-4-phenyl-6-methoxy-2(1H)-quinazolinone

Chemical Property of 6-methoxy-4-phenyl-1-(2,2,2-trifluoroethyl)-2-(1H)-quinazolinone

Chemical Property:

• Vapor Pressure: 1.01E-07mmHg at 25°C
• Boiling Point: 433.6°Cat760mmHg
• Flash Point: 216°C
• PSA: 44.12000
• Density: 1.32g/cm³
• LogP: 3.63440

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-methoxy-4-phenyl-1-(2,2,2-trifluoroethyl)-2-(1H)-quinazolinone

There total 4 articles about 6-methoxy-4-phenyl-1-(2,2,2-trifluoroethyl)-2-(1H)-quinazolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-1,1,1-trifluoroethane (421-06-7) + 4-Phenyl-6-methoxy-2(1H)-quinazolinone (13961-59-6) → 1-(2,2,2-Trifluoroethyl)-4-phenyl-6-methoxy-2(1H)-quinazolinone (49830-89-9)

Guidance literature:

With potassium iodide; In N-methyl-acetamide; water;

Reference yield:

→ 1-(2,2,2-Trifluoroethyl)-4-phenyl-6-methoxy-2(1H)-quinazolinone (49830-89-9)

Guidance literature:

entspr. 2-Trichloracetamido-benzophenon (II), NH4OAc;

Reference yield:

→ 1-(2,2,2-Trifluoroethyl)-4-phenyl-6-methoxy-2(1H)-quinazolinone (49830-89-9) + 1-(2,2,2-trifluoroethyl)-4-phenyl-2(1H)-quinazolinone (40852-52-6)

Guidance literature:

upstream raw materials:

2-bromo-1,1,1-trifluoroethane

4-Phenyl-6-methoxy-2(1H)-quinazolinone

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