Dehydrooogoniol

Base Information

Chemical Name:Dehydrooogoniol
CAS No.:82251-59-0
Molecular Formula:C₂₉H₄₆O₅
Molecular Weight:474.681
Hs Code.:

Synonyms:3,11,15,29-tetrahydroxystigmasta-5,24(28)-dien-7-one;dehydroogoniol

Suppliers and Price of Dehydrooogoniol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Dehydrooogoniol

Chemical Property:

Vapor Pressure:2.5E-19mmHg at 25°C
Boiling Point:644.4°Cat760mmHg
Flash Point:357.5°C
PSA：97.99000
Density:1.16g/cm³
LogP:4.03790
XLogP3:3.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:474.33452456
Heavy Atom Count:34
Complexity:846

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(=CCO)CCC(C)C1CC(C2C1(CC(C3C2C(=O)C=C4C3(CCC(C4)O)C)O)C)O
Isomeric SMILES:C[C@H](CC/C(=C\CO)/C(C)C)[C@H]1C[C@H]([C@@H]2[C@@]1(C[C@H]([C@H]3[C@H]2C(=O)C=C4[C@@]3(CC[C@@H](C4)O)C)O)C)O

Technology Process of Dehydrooogoniol

There total 82 articles about Dehydrooogoniol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 125631-97-2
C₃₃H₄₆O₉

: 82251-59-0
dehydro-oogoniol

Guidance literature:: With potassium carbonate; In methanol; for 1h; Ambient temperature;
DOI:10.1016/S0040-4020(01)82010-X

Reference yield:

: 57-83-0
Progesterone

: 82251-59-0
dehydro-oogoniol

Guidance literature:: Multi-step reaction with 18 steps

1: Aspergillus giganteus (ATCC 10059)

2: acetic anhydride / 2 h / Heating

3: 70 percent / p-toluenesulfonic acid / benzene / 1.5 h / Heating

4: 69 percent / NaBH₄ / ethanol / Ambient temperature

5: 86 percent / p-toluenesulfonic acid / ethanol

6: 83 percent / Et₃N, dimethylamino pyridine / CH₂Cl₂ / Ambient temperature

7: 72 percent / potassium t-amylate / benzene; toluene / 3 h / Ambient temperature

8: NaI, trimethylsilylchloride, sodium thiosulfate / acetonitrile / Ambient temperature

9: 430 mg / NaH / tetrahydrofuran / 1.5 h / Heating

10: 91 percent / H₂ / Pd-BaSO₄ / ethyl acetate / 3 h / Ambient temperature

11: 85 percent / NaH / tetrahydrofuran / 4 h / Heating

12: 1.) (iBu)2AlH, 2.) dil. acetic acid / 1.) toluene, r.t., 2 h, 2.) MeOH-THF, r.t.

13: 63 mg / pyridine / 72 h / Ambient temperature

14: 1.) (iBu)2AlH, 2.) aq. acetic acid, CHCl₃ / 1.) toluene, 1.5 h, r.t., 2.) r.t., 3 h

15: 92 percent / pyridine / 72 h / Ambient temperature

16: 56 percent / CrO₃, dimethylpyrazole / CH₂Cl₂ / 4 h / -15 °C

17: 74 percent / H₂O, K₂CO₃ / methanol / 24 h / Ambient temperature

18: aq. KOH / methanol / 12 h / 45 °C

With 1,3-dimethyl-1H-pyrazole; chromium(VI) oxide; dmap; potassium hydroxide; sodium tetrahydroborate; chloro-trimethyl-silane; chloroform; water; hydrogen; sodium hydride; diisobutylaluminium hydride; potassium 2-methylbutan-2-olate; potassium carbonate; toluene-4-sulfonic acid; sodium thiosulfate; acetic acid; triethylamine; sodium iodide; palladium on barium sulfate; In tetrahydrofuran; pyridine; methanol; ethanol; dichloromethane; acetic anhydride; ethyl acetate; toluene; acetonitrile; benzene;
DOI:10.1016/0039-128X(89)90019-6

Reference yield:

: 82538-36-1
11α,15β-dihydroxypregn-4-ene-3,20-dione

: 82251-59-0
dehydro-oogoniol

Guidance literature:: Multi-step reaction with 17 steps

1: acetic anhydride / 2 h / Heating

2: 70 percent / p-toluenesulfonic acid / benzene / 1.5 h / Heating

3: 69 percent / NaBH₄ / ethanol / Ambient temperature

4: 86 percent / p-toluenesulfonic acid / ethanol

5: 83 percent / Et₃N, dimethylamino pyridine / CH₂Cl₂ / Ambient temperature

6: 72 percent / potassium t-amylate / benzene; toluene / 3 h / Ambient temperature

7: NaI, trimethylsilylchloride, sodium thiosulfate / acetonitrile / Ambient temperature

8: 430 mg / NaH / tetrahydrofuran / 1.5 h / Heating

9: 91 percent / H₂ / Pd-BaSO₄ / ethyl acetate / 3 h / Ambient temperature

10: 85 percent / NaH / tetrahydrofuran / 4 h / Heating

11: 1.) (iBu)2AlH, 2.) dil. acetic acid / 1.) toluene, r.t., 2 h, 2.) MeOH-THF, r.t.

12: 63 mg / pyridine / 72 h / Ambient temperature

13: 1.) (iBu)2AlH, 2.) aq. acetic acid, CHCl₃ / 1.) toluene, 1.5 h, r.t., 2.) r.t., 3 h

14: 92 percent / pyridine / 72 h / Ambient temperature

15: 56 percent / CrO₃, dimethylpyrazole / CH₂Cl₂ / 4 h / -15 °C

16: 74 percent / H₂O, K₂CO₃ / methanol / 24 h / Ambient temperature

17: aq. KOH / methanol / 12 h / 45 °C

With 1,3-dimethyl-1H-pyrazole; chromium(VI) oxide; dmap; potassium hydroxide; sodium tetrahydroborate; chloro-trimethyl-silane; chloroform; water; hydrogen; sodium hydride; diisobutylaluminium hydride; potassium 2-methylbutan-2-olate; potassium carbonate; toluene-4-sulfonic acid; sodium thiosulfate; acetic acid; triethylamine; sodium iodide; palladium on barium sulfate; In tetrahydrofuran; pyridine; methanol; ethanol; dichloromethane; acetic anhydride; ethyl acetate; toluene; acetonitrile; benzene;
DOI:10.1016/0039-128X(89)90019-6