N-(4-Bromophenyl)-1-piperidinepentanamide

Base Information

Chemical Name:N-(4-Bromophenyl)-1-piperidinepentanamide
CAS No.:874449-94-2
Molecular Formula:C₁₆H₂₃BrN₂O
Molecular Weight:339.275
Hs Code.:
DSSTox Substance ID:DTXSID30704665
Wikidata:Q82637148
Mol file:874449-94-2.mol

Synonyms:N-(4-Bromophenyl)-1-piperidinepentanamide;874449-94-2;SCHEMBL14006053;DTXSID30704665;FT-0719746;N-(4-Bromophenyl)-5-(piperidin-1-yl)pentanamide

Suppliers and Price of N-(4-Bromophenyl)-1-piperidinepentanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

A1 Biochem Labs
N-(4-Bromophenyl)-5-piperidin-1-ylpentanamide 95%
1 g
$ 700.00

Total 2 raw suppliers

Chemical Property of N-(4-Bromophenyl)-1-piperidinepentanamide

Chemical Property:

PSA：32.34000
LogP:4.05470
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:338.09938
Heavy Atom Count:20
Complexity:284

Purity/Quality:

97% ^*data from raw suppliers

N-(4-Bromophenyl)-5-piperidin-1-ylpentanamide 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)CCCCC(=O)NC2=CC=C(C=C2)Br

Technology Process of N-(4-Bromophenyl)-1-piperidinepentanamide

There total 4 articles about N-(4-Bromophenyl)-1-piperidinepentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 110-89-4
piperidine

: 948883-07-6
5-bromo-N-(4-bromophenyl)pentanamide

: 874449-94-2
5-(piperidin-1-yl)pentanoic acid (4-bromophenyl)amide

Guidance literature:: With triethylamine; sodium iodide; In N,N-dimethyl-formamide; for 16h; Reflux; Inert atmosphere;
DOI:10.1016/j.ejmech.2015.03.025

Reference yield:

: 2067-33-6
5-bromopentanoic acid

: 874449-94-2
5-(piperidin-1-yl)pentanoic acid (4-bromophenyl)amide

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl dichloride / 0.75 h / 20 °C / Inert atmosphere

2: triethylamine / dichloromethane / -78 °C / Inert atmosphere

3: sodium iodide; triethylamine / N,N-dimethyl-formamide / 16 h / Reflux; Inert atmosphere

With oxalyl dichloride; triethylamine; sodium iodide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2015.03.025

Reference yield:

: 4509-90-4
5-bromovaleroyl chloride

: 874449-94-2
5-(piperidin-1-yl)pentanoic acid (4-bromophenyl)amide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / -78 °C / Inert atmosphere

2: sodium iodide; triethylamine / N,N-dimethyl-formamide / 16 h / Reflux; Inert atmosphere

With triethylamine; sodium iodide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2015.03.025