1H-1,2,3-Triazole-4-carboxylic acid, 5-methyl-1-(1-naphthalenyl)-

Base Information

Chemical Name:1H-1,2,3-Triazole-4-carboxylic acid, 5-methyl-1-(1-naphthalenyl)-
CAS No.:70292-10-3
Molecular Formula:C₁₄H₁₁N₃O₂
Molecular Weight:253.26
Hs Code.:
DSSTox Substance ID:DTXSID60220545
Wikidata:Q83097817

Synonyms:70292-10-3;BRN 0805647;5-Methyl-1-(1-naphthalenyl)-1H-1,2,3-triazole-4-carboxylic acid;1H-1,2,3-Triazole-4-carboxylic acid, 5-methyl-1-(1-naphthalenyl)-;5-Methyl-1-(naphthalen-1-yl)-1H-1,2,3-triazole-4-carboxylic acid;SCHEMBL20604102;DTXSID60220545;AKOS005874971;LS-155863;5-methyl-1-(1-naphthyl)-1,2,3-triazol-4-carboxylic acid

Suppliers and Price of 1H-1,2,3-Triazole-4-carboxylic acid, 5-methyl-1-(1-naphthalenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1H-1,2,3-Triazole-4-carboxylic acid, 5-methyl-1-(1-naphthalenyl)-

Chemical Property:

Vapor Pressure:7.77E-12mmHg at 25°C
Boiling Point:524.7°Cat760mmHg
Flash Point:271.1°C
Density:1.35g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:253.085126602
Heavy Atom Count:19
Complexity:350

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N=NN1C2=CC=CC3=CC=CC=C32)C(=O)O

Technology Process of 1H-1,2,3-Triazole-4-carboxylic acid, 5-methyl-1-(1-naphthalenyl)-

There total 4 articles about 1H-1,2,3-Triazole-4-carboxylic acid, 5-methyl-1-(1-naphthalenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 6921-40-0
1-azidonaphthalene

: 141-97-9
ethyl acetoacetate

: 70292-10-3
5-methyl-1-(naphthalen-1-yl)-1H-1,2,3-triazole-4-carboxylic acid

Guidance literature:: With sodium ethanolate; In ethanol; at 80 ℃;
DOI:10.1021/acs.jmedchem.8b01408

Reference yield: 72.0%

: 70292-10-3
5-methyl-1-(naphthalen-1-yl)-1H-1,2,3-triazole-4-carboxylic acid

Guidance literature:: With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 1h;

With sodium azide; In water; at 0 ℃; for 1h;

With sodium ethanolate; In methanol; at 80 ℃;

Reference yield:

: 134-32-7
1-amino-naphthalene

: 70292-10-3
5-methyl-1-(naphthalen-1-yl)-1H-1,2,3-triazole-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium nitrite; hydrogenchloride / water / 0 - 5 °C

1.2: 0 - 5 °C

2.1: sodium ethanolate; ethanol

With hydrogenchloride; ethanol; sodium ethanolate; sodium nitrite; In water;