1-Azidonaphthalene

Base Information

• Chemical Name: 1-Azidonaphthalene
• CAS No.: 6921-40-0
• Molecular Formula: C10H7N3
• Molecular Weight: 169.186
• Hs Code.: 2929909090
• DSSTox Substance ID: DTXSID80988913
• Nikkaji Number: J81.296J
• Wikidata: Q82977635
• ChEMBL ID: CHEMBL3236185
• Mol file: 6921-40-0.mol

Synonyms:1-Azidonaphthalene;1-Naphthyl azide;6921-40-0;Naphthalene, 1-azido-;naphthyl azide;.alpha.-Naphthyl azide;dicaesium 4,4'-methanediylbis(3-hydroxynaphthalene-2-carboxylate);CHEMBL3236185;SCHEMBL13588508;DTXSID80988913;EN300-68418

Chemical Property of 1-Azidonaphthalene

Chemical Property:

• Melting Point: 12°C
• Refractive Index: 1.6550
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 49.75000
• Density: g/cm³
• LogP: 3.23436
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 169.063997236
• Heavy Atom Count: 13
• Complexity: 220

Purity/Quality:

99% ^*data from raw suppliers

1-Azidonaphthalene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2N=[N+]=[N-]

Technology Process of 1-Azidonaphthalene

There total 16 articles about 1-Azidonaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-amino-naphthalene (134-32-7) → 1-azidonaphthalene (6921-40-0)

Guidance literature:

With tert.-butylnitrite; trimethylsilylazide; In acetonitrile; at 0 - 20 ℃; for 1h;

DOI:10.1039/c3cc43838d

Reference yield: 98.0%

1-Naphthylboronic acid (13922-41-3) → 1-azidonaphthalene (6921-40-0)

Guidance literature:

With sodium azide; copper(II) sulfate; In methanol; at 20 ℃; for 5h;

DOI:10.1016/j.tetlet.2007.03.107

Reference yield: 88.0%

1-amino-naphthalene (134-32-7) + azidotris(diethylamino)phosphonium bromide → 1-azidonaphthalene (6921-40-0) + N,N,N',N',N'',N''-hexaethylphosphonimidic triamide (74400-91-2)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.75h;

DOI:10.1016/S0040-4039(02)01444-2

upstream raw materials:

1-amino-naphthalene

naphthalene

1-Naphthylboronic acid

trans-2-bromo-1,2,3,4-tetrahydronaphthalen-1-ol

Downstream raw materials:

1-amino-naphthalene

di-t-butyl 1-(1-naphthyl)-1H-1,2,3-triazole-4,5-dicarboxylate

5-tert-butyl-3-(1-naphthyl)-3H-1,2,3,4-triazaphosphole

dibenzo[a,h]phenazine