[(2S,3R)-3-(methylsulfonyloxymethyl)-2-bicyclo[2.2.1]hept-5-enyl]methyl methanesulfonate

Base Information

Chemical Name:[(2S,3R)-3-(methylsulfonyloxymethyl)-2-bicyclo[2.2.1]hept-5-enyl]methyl methanesulfonate
CAS No.:2434-86-8
Molecular Formula:C₁₁H₁₈O₆S₂
Molecular Weight:310.392
Hs Code.:
NSC Number:81679,81678

Synonyms:NSC81678;2590-37-6;NSC81679;NSC-81678;NSC-81679;2434-86-8

Suppliers and Price of [(2S,3R)-3-(methylsulfonyloxymethyl)-2-bicyclo[2.2.1]hept-5-enyl]methyl methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of [(2S,3R)-3-(methylsulfonyloxymethyl)-2-bicyclo[2.2.1]hept-5-enyl]methyl methanesulfonate

Chemical Property:

Vapor Pressure:2.99E-10mmHg at 25°C
Refractive Index:1.523
Boiling Point:516.2°Cat760mmHg
Flash Point:266°C
Density:1.358g/cm³
XLogP3:0.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:310.05448064
Heavy Atom Count:19
Complexity:501

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)OCC1C2CC(C1COS(=O)(=O)C)C=C2
Isomeric SMILES:CS(=O)(=O)OC[C@@H]1[C@@H](C2CC1C=C2)COS(=O)(=O)C

Technology Process of [(2S,3R)-3-(methylsulfonyloxymethyl)-2-bicyclo[2.2.1]hept-5-enyl]methyl methanesulfonate

There total 7 articles about [(2S,3R)-3-(methylsulfonyloxymethyl)-2-bicyclo[2.2.1]hept-5-enyl]methyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 941567-71-1,448922-61-0
(1R,2S,3R,4S)-bicyclo[2.2.1]hept-5-ene-2,3-dimethanol

: 124-63-0
methanesulfonyl chloride

: 2434-86-8,2434-87-9,77983-96-1,91967-21-4,2590-37-6
Methanesulfonic acid (1S,2R,3S,4R)-3-methanesulfonyloxymethyl-bicyclo[2.2.1]hept-5-en-2-ylmethyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1021/jacs.7b11960

Reference yield: 88.0%

: 124-63-0
methanesulfonyl chloride

: 85-39-2,699-95-6,699-96-7,699-97-8,54423-36-8,78037-77-1,79516-58-8,111321-65-4,448922-61-0
trans-5-norbornene-2,3-dimethanol

: 2434-86-8,2434-87-9,2590-37-6,77983-96-1,91967-21-4
Methanesulfonic acid (2R,3R)-3-methanesulfonyloxymethyl-bicyclo[2.2.1]hept-5-en-2-ylmethyl ester

Guidance literature:: at 0 ℃; for 8h;
DOI:10.1021/ja00404a028

Reference yield:

: 129-64-6
3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride

: 2434-86-8,2434-87-9,77983-96-1,91967-21-4,2590-37-6
Methanesulfonic acid (1S,2R,3S,4R)-3-methanesulfonyloxymethyl-bicyclo[2.2.1]hept-5-en-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / LiAlH₄ / tetrahydrofuran / 5.5 h / 20 °C

2: 83 percent / Et₃N / CH₂Cl₂ / 2 h / 0 °C

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo0620260