1H-Indol-3-ol

Base Information

Chemical Name:1H-Indol-3-ol
CAS No.:480-93-3
Molecular Formula:C8H7NO
Molecular Weight:133.15
Hs Code.:2933990090
European Community (EC) Number:689-424-0
DSSTox Substance ID:DTXSID20861998
Nikkaji Number:J6.171I
Wikipedia:Indoxyl
Wikidata:Q423256
Metabolomics Workbench ID:38465
Mol file:480-93-3.mol

Synonyms:1H-indol-3-ol;indoxyl

Suppliers and Price of 1H-Indol-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Hydroxyindole
100mg
$ 145.00

Medical Isotopes, Inc.
3-Hydroxyindole
1 g
$ 1110.00

Apolloscientific
3-Hydroxy-1H-indole
250mg
$ 560.00

Apolloscientific
3-Hydroxy-1H-indole
100mg
$ 363.00

American Custom Chemicals Corporation
3-HYDROXYINDOLE 95.00%
1G
$ 843.59

AHH
3-Hydroxyindole 98%
5g
$ 768.00

Total 36 raw suppliers

Chemical Property of 1H-Indol-3-ol

Chemical Property:

Appearance/Colour:yellow -green powder.
Melting Point:85-87 °C
Refractive Index:1.5260 (estimate)
Boiling Point:343.192 °C at 760 mmHg
PKA:10.10±0.40(Predicted)
Flash Point:161.357 °C
PSA：36.02000
Density:1.327 g/cm³
LogP:1.87350
Storage Temp.:Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly, Sonicated)
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:133.052763847
Heavy Atom Count:10
Complexity:126

Purity/Quality:

97% ^*data from raw suppliers

3-Hydroxyindole ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: R36/37/38:Irritating to eyes, respiratory system and skin.;
Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CN2)O
Uses 1H-INDOL-3-OL is a mutation product of toluene-4-monooxygenase (T4MO), that gets spontaneously converted to indigo. Used in the preparation of indolyl-oxadiazoles with anticonvulsant activity. 3-Hydroxyindole is a mutation product of toluene-4-monooxygenase (T4MO), that gets spontaneously converted to indigo. Used in the preparation of indolyl-oxadiazoles with anticonvulsant activity.

Technology Process of 1H-Indol-3-ol

There total 72 articles about 1H-Indol-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 4127-53-1
3-methylbenzo[c]isoxazole

: 480-93-3
indoxyl

Guidance literature:: at 575 ℃;
DOI:10.24820/ARK.5550190.P011.239

Reference yield:

: 16714-26-4
1-(2-azido-phenyl)-ethanone

: 3260-61-5
indolin-3-one

: 480-93-3
indoxyl

Guidance literature:: at 650 ℃; under 0.02 Torr; Flash vacuum pyrolysis;
DOI:10.1055/s-0029-1218668

Reference yield:

: 120-72-9
indole

: 16990-73-1
2-Hydroxyindole

: 480-93-3
indoxyl

: 479-41-4
indirubin

: 482-89-3,12626-73-2
1H,1H'-2,2'-Biindolylidene-3,3'-dione

Guidance literature:: With P₄₅₀ BM-3 mutant; NADPH; In water; dimethyl sulfoxide; for 0.333333h; pH=8.2; Further Variations:; Reagents; Kinetics;
DOI:10.1002/(SICI)1521-3765(20000502)6:9<1531::AID-CHEM1531>3.3.CO;2-4