4-Oxoretinol

Base Information

Chemical Name:4-Oxoretinol
CAS No.:62702-55-0
Molecular Formula:C20H28O2
Molecular Weight:300.441
Hs Code.:
UNII:6FFM6M3NPT
DSSTox Substance ID:DTXSID80866949
Nikkaji Number:J648.935D
Wikidata:Q27093646
Metabolomics Workbench ID:42002
Mol file:62702-55-0.mol

Synonyms:4-ketoretinol;4-oxoretinol

Suppliers and Price of 4-Oxoretinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-KetoRetinol(~90%)
25mg
$ 760.00

Medical Isotopes, Inc.
9-cis-4-Ketoretinol
1 mg
$ 925.00

Medical Isotopes, Inc.
9-cis-4-Ketoretinol
5 mg
$ 2400.00

Medical Isotopes, Inc.
4-Ketoretinol
25 mg
$ 2000.00

American Custom Chemicals Corporation
4-KETORETINOL 95.00%
50MG
$ 1871.10

American Custom Chemicals Corporation
4-KETORETINOL 95.00%
5MG
$ 774.40

American Custom Chemicals Corporation
4-KETO RETINOL 95.00%
5MG
$ 501.12

Total 8 raw suppliers

Chemical Property of 4-Oxoretinol

Chemical Property:

Vapor Pressure:1.27E-10mmHg at 25°C
Melting Point:102-106oC
Boiling Point:465.5°Cat760mmHg
PKA:14.09±0.10(Predicted)
Flash Point:198°C
PSA：37.30000
Density:1.013g/cm³
LogP:4.68930
Storage Temp.:Amber Vial, -20?C Freezer
Solubility.:Acetonitrile (Slightly), Chloroform (Slightly)
XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:300.208930132
Heavy Atom Count:22
Complexity:567

Purity/Quality:

98%Min ^*data from raw suppliers

4-KetoRetinol(~90%) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(CCC1=O)(C)C)C=CC(=CC=CC(=CCO)C)C
Isomeric SMILES:CC1=C(C(CCC1=O)(C)C)/C=C/C(=C/C=C/C(=C/CO)/C)/C
Uses 4-KETORETINOL activate gene expression through binding to nuclear receptor proteins. They are useful for treating leukemia, lymphoma, squamous cell carcinoma, deep (cystic) acne, psoriasis, and photodamaged or aging skin. A metabolite of Retinol.

Technology Process of 4-Oxoretinol

There total 9 articles about 4-Oxoretinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 33532-44-4,71423-69-3
4-ketoretinal

: 62702-55-0
4-ketoretinol

Guidance literature:: With sodium hydroxide; sodium tetrahydroborate; In tetrahydrofuran; methanol; at 0 ℃; for 1h;
DOI:10.1021/ja00177a044

Reference yield: 90.0%

: 33532-44-4
4-keto-all-trans-retinal

: 62702-55-0
all-trans-4-oxoretinol

Guidance literature:: With lithium tris[(3-ethyl-3-pentyl)oxy]aluminohydride;

Reference yield:

: 68-26-8
RETINOL

: 512-39-0
5,6-Epoxyretinol

: 79-80-1
vitamin A₂

: 62702-55-0
all-trans-4-oxoretinol

: 5,8-Epoxyretinol

Guidance literature:: With dihydrogen peroxide; iron(III) tetraphenylporphyrin; In methanol; dichloromethane; at 30 ℃; for 24h; Yield given. Further byproducts given. Yields of byproduct given;