1-methyl-1H-pyrazolo[3,4-d]pyrimidine-4,6(2H,5H)-dithione

Base Information

• Chemical Name: 1-methyl-1H-pyrazolo[3,4-d]pyrimidine-4,6(2H,5H)-dithione
• CAS No.: 30682-70-3
• Molecular Formula: C6H6 N4 S2
• Molecular Weight: 198.2686
• Mol file: 30682-70-3.mol

Synonyms:1H-Pyrazolo[3,4-d]pyrimidine-4,6-dithiol,1-methyl- (6CI,8CI); NSC 515405

Chemical Property of 1-methyl-1H-pyrazolo[3,4-d]pyrimidine-4,6(2H,5H)-dithione

Chemical Property:

• Vapor Pressure: 0.000568mmHg at 25°C
• Boiling Point: 311.3°Cat760mmHg
• Flash Point: 142.1°C
• Density: 1.74g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-methyl-1H-pyrazolo[3,4-d]pyrimidine-4,6(2H,5H)-dithione

There total 4 articles about 1-methyl-1H-pyrazolo[3,4-d]pyrimidine-4,6(2H,5H)-dithione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.9%

carbon disulfide (75-15-0,12122-00-8) + 5-amino-4-cyano-1-methylpyrazole (5334-41-8) → 1-methylpyrazolo[3,4-d]pyrimidin-4,6(5H,7H)-dithione (30682-70-3)

Guidance literature:

With pyridine; for 10h; Heating;

Reference yield:

1-Methyl-1H-pyrazolo<3,4-d>pyrimidine-4,6(5H,7H)-dione (5401-15-0) → 1-methylpyrazolo[3,4-d]pyrimidin-4,6(5H,7H)-dithione (30682-70-3)

Guidance literature:

Multi-step reaction with 2 steps

1: PCl₅; POCl₃

2: ethanol

With ethanol; phosphorus pentachloride; trichlorophosphate;

DOI:10.1021/jo01100a025

Reference yield:

4,6-dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine (98141-42-5) + thiourea (17356-08-0) → 1-methylpyrazolo[3,4-d]pyrimidin-4,6(5H,7H)-dithione (30682-70-3)

Guidance literature:

With ethanol;

DOI:10.1021/jo01100a025

upstream raw materials:

4,6-dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

thiourea

carbon disulfide

5-amino-4-cyano-1-methylpyrazole

Downstream raw materials:

1-methyl-4,6-dimethylthiopyrazolo[3,4-d]pyrimidine