3,3'-Dibromo-1,1'-difluoro-2,2'-binaphthalene

Base Information

Chemical Name:3,3'-Dibromo-1,1'-difluoro-2,2'-binaphthalene
CAS No.:874907-49-0
Molecular Formula:C20H10Br2F2
Molecular Weight:448.104
Hs Code.:
DSSTox Substance ID:DTXSID601250777
Nikkaji Number:J2.264.002J

Synonyms:DTXSID601250777;874907-49-0;3,3'-Dibromo-1,1'-difluoro-2,2'-binaphthalene

Suppliers and Price of 3,3'-Dibromo-1,1'-difluoro-2,2'-binaphthalene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3,3'-Dibromo-1,1'-difluoro-2,2'-binaphthalene

Chemical Property:

XLogP3:7.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:447.90968
Heavy Atom Count:24
Complexity:405

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(C(=C2F)C3=C(C4=CC=CC=C4C=C3Br)F)Br

Technology Process of 3,3'-Dibromo-1,1'-difluoro-2,2'-binaphthalene

There total 1 articles about 3,3'-Dibromo-1,1'-difluoro-2,2'-binaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 317-79-3
2-bromo-1-fluoronaphthalene

: 874907-49-0
3,3'-dibromo-1,1'-difluoro-2,2'-binaphthyl

Guidance literature:: Multi-step reaction with 3 steps

1.1: 89 percent / 2,2,6,6-tetramethylpiperidine; butyllithium / tetrahydrofuran; hexane / 6 h / -75 °C

2.1: diisopropylamine; butyllithium / tetrahydrofuran; hexane / 2 h / -75 °C

2.2: 80 percent / iodine / tetrahydrofuran; hexane

3.1: sec-butyllithium / tetrahydrofuran; hexane / 2 h / -75 °C

3.2: cupric bromide / tetrahydrofuran; hexane / 0.75 h / -75 °C

3.3: 66 percent / nitrobenzene / tetrahydrofuran; hexane / -75 - 25 °C

With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; sec.-butyllithium; diisopropylamine; In tetrahydrofuran; hexane;
DOI:10.1002/ejoc.200500514

Reference yield: 70.0%

: 874907-49-0
3,3'-dibromo-1,1'-difluoro-2,2'-binaphthyl

: 644-97-3
Dichlorophenylphosphine

: 1,13-difluoro-7-phenyl-7H-benzo[f]naphtho[2,3-b]phosphindole

Guidance literature:: 3,3'-dibromo-1,1'-difluoro-2,2'-binaphthyl; With n-butyllithium; In tetrahydrofuran; hexane; at -75 ℃;

Dichlorophenylphosphine; In tetrahydrofuran; hexane;
DOI:10.1002/ejoc.200500514

Reference yield: 67.0%

: 874907-49-0
3,3'-dibromo-1,1'-difluoro-2,2'-binaphthyl

: 16523-54-9
chlorodicyclohexylphosphane

: 3,3'-bis(dicyclohexylphosphanyl)-1,1'-difluoro-2,2'-binaphthyl

Guidance literature:: 3,3'-dibromo-1,1'-difluoro-2,2'-binaphthyl; With n-butyllithium; In tetrahydrofuran; hexane; at -75 ℃;

chlorodicyclohexylphosphane; In tetrahydrofuran; hexane;
DOI:10.1002/ejoc.200500514