(2-Fluorophenyl)(naphthalen-1-yl)methanone

Base Information

Chemical Name:(2-Fluorophenyl)(naphthalen-1-yl)methanone
CAS No.:1543-59-5
Molecular Formula:C17H11 F O
Molecular Weight:250.272
Hs Code.:
NSC Number:97659
DSSTox Substance ID:DTXSID30294697
Wikidata:Q82034109
Mol file:1543-59-5.mol

Synonyms:1543-59-5;(2-fluorophenyl)(naphthalen-1-yl)methanone;NSC97659;NCIOpen2_006270;1-(2-fluorobenzoyl)naphthalene;DTXSID30294697;NSC-97659;(2-fluorophenyl)(1-naphthyl)methanone;AKOS012007975;(2-Fluoro-phenyl)-naphthalen-1-yl-methanone

Suppliers and Price of (2-Fluorophenyl)(naphthalen-1-yl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of (2-Fluorophenyl)(naphthalen-1-yl)methanone

Chemical Property:

Vapor Pressure:2.28E-07mmHg at 25°C
Boiling Point:423.1°C at 760 mmHg
Flash Point:185.3°C
Density:1.215g/cm³
XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:250.079393132
Heavy Atom Count:19
Complexity:327

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CC=C2C(=O)C3=CC=CC=C3F

Technology Process of (2-Fluorophenyl)(naphthalen-1-yl)methanone

There total 11 articles about (2-Fluorophenyl)(naphthalen-1-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 462-06-6
fluorobenzene

: 879-18-5
naphthalene-1-carbonic acid chloride

: 1543-58-4
1-(3-fluorobenzoyl)naphthalene

: 1543-59-5
1-(2-fluorobenzoyl)naphthalene

: 147022-30-8
(4-fluorophenyl)(naphthalene-4-yl)methanone

Guidance literature:: With aluminum (III) chloride; In dichloromethane; at 40 ℃; for 4h;
DOI:10.1007/s11224-019-01368-z

Reference yield:

: 147022-30-8
(4-fluorophenyl)(naphthalene-4-yl)methanone

: 462-06-6
fluorobenzene

: 1543-58-4
1-(3-fluorobenzoyl)naphthalene

: 1543-59-5
1-(2-fluorobenzoyl)naphthalene

Guidance literature:: With polyphosphoric acid; at 80 ℃; for 6h; Time;
DOI:10.1007/s11224-019-01368-z

Reference yield:

: 642-29-5
1-benzoylnaphthalene

: 1543-60-8
2-(2-fluorobenzoyl)naphthalene

: 1543-59-5
1-(2-fluorobenzoyl)naphthalene

Guidance literature:: Multi-step reaction with 2 steps

1: polyphosphoric acid / 6 h / 140 °C

2: aluminum (III) chloride / dichloromethane / 8 h / 20 °C

With aluminum (III) chloride; In dichloromethane; 2: |Friedel-Crafts Acylation;
DOI:10.1007/s11224-019-01368-z