1-[2-Phenyl-2-(thiophen-2-yl)ethyl]pyrrolidine-2,5-dione

Base Information

Chemical Name:1-[2-Phenyl-2-(thiophen-2-yl)ethyl]pyrrolidine-2,5-dione
CAS No.:87520-01-2
Molecular Formula:C16H15NO2S
Molecular Weight:
Hs Code.:
DSSTox Substance ID:DTXSID10527258

Synonyms:87520-01-2;DTXSID10527258;1-[2-Phenyl-2-(thiophen-2-yl)ethyl]pyrrolidine-2,5-dione

Suppliers and Price of 1-[2-Phenyl-2-(thiophen-2-yl)ethyl]pyrrolidine-2,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-[2-Phenyl-2-(thiophen-2-yl)ethyl]pyrrolidine-2,5-dione

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:285.08234989
Heavy Atom Count:20
Complexity:363

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1=O)CC(C2=CC=CC=C2)C3=CC=CS3

Technology Process of 1-[2-Phenyl-2-(thiophen-2-yl)ethyl]pyrrolidine-2,5-dione

There total 1 articles about 1-[2-Phenyl-2-(thiophen-2-yl)ethyl]pyrrolidine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 188290-36-0,8014-23-1,25233-34-5
thiophene

: 108-30-5
succinic acid anhydride

: 7568-93-6,1936-63-6
2-Amino-1-phenylethanol

: 87520-01-2
2-<2-(2,5-dioxopyrrolidin-1-yl)-1-phenylethyl>thiophen

Guidance literature:: Yield given. Multistep reaction;
DOI:10.1021/jo00173a053

Reference yield:

: 87520-01-2
2-<2-(2,5-dioxopyrrolidin-1-yl)-1-phenylethyl>thiophen

: 87519-66-2
4,5,9,9aα-tetrahydro-4α-phenylthieno<2,3-g>indolizin-7(8H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: NaBH₄, CH₃SO₃H

2: ethereal HCl / ethanol

With hydrogenchloride; sodium tetrahydroborate; methanesulfonic acid; In ethanol;
DOI:10.1021/jo00173a053

Reference yield:

: 87520-01-2
2-<2-(2,5-dioxopyrrolidin-1-yl)-1-phenylethyl>thiophen

: 87519-67-3
4,5,9,9aα-tetrahydro-4β-phenylthieno<2,3-g>indolizin-7(8H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: NaBH₄, CH₃SO₃H

2: ethereal HCl / ethanol

With hydrogenchloride; sodium tetrahydroborate; methanesulfonic acid; In ethanol;
DOI:10.1021/jo00173a053