1,2-Benzenedicarboxylic acid, 4-[[6-[3,5-bis(decyloxy)phenoxy]-1-oxohexyl][4-(methoxycarbonyl)phenyl ]amino]-, dimethyl ester

Base Information

• Chemical Name: 1,2-Benzenedicarboxylic acid, 4-[[6-[3,5-bis(decyloxy)phenoxy]-1-oxohexyl][4-(methoxycarbonyl)phenyl ]amino]-, dimethyl ester
• CAS No.: 875211-06-6
• Molecular Formula: C50H71NO10
• Molecular Weight: 846.114
• Mol file: 875211-06-6.mol

Synonyms:

Chemical Property of 1,2-Benzenedicarboxylic acid, 4-[[6-[3,5-bis(decyloxy)phenoxy]-1-oxohexyl][4-(methoxycarbonyl)phenyl ]amino]-, dimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-Benzenedicarboxylic acid, 4-[[6-[3,5-bis(decyloxy)phenoxy]-1-oxohexyl][4-(methoxycarbonyl)phenyl ]amino]-, dimethyl ester

There total 8 articles about 1,2-Benzenedicarboxylic acid, 4-[[6-[3,5-bis(decyloxy)phenoxy]-1-oxohexyl][4-(methoxycarbonyl)phenyl ]amino]-, dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

6-bromohexanoic acid N-(4-methoxycarbonylphenyl)-N-(3,4-di(methoxycarbonyl)phenyl)amide (912806-31-6) + 3,5-didecyloxyphenol (875210-88-1) → 4-[[6-(3,5-bis-decyloxy-phenoxy)-hexanoyl]-(4-methoxycarbonyl-phenyl)-amino]-phthalic acid dimethyl ester (875211-06-6)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; potassium carbonate; In cyclohexanone; for 5h; Heating;

DOI:10.1021/jm060468y

Reference yield:

N-(4-methoxycarbonylphenyl)-N-(3,4-di(methoxycarbonyl)phenyl)amine (912806-27-0) → 4-[[6-(3,5-bis-decyloxy-phenoxy)-hexanoyl]-(4-methoxycarbonyl-phenyl)-amino]-phthalic acid dimethyl ester (875211-06-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / dibutyl ether / 2 h / 20 °C

1.2: 85 percent / dibutyl ether / 4 h / Heating

2.1: 43 percent / potassium carbonate; n-Bu₄NI / cyclohexanone / 5 h / Heating

With tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; In dibutyl ether; cyclohexanone;

DOI:10.1021/jm060468y

Reference yield:

N-(4-ethoxycarbonylphenyl)-N-(3,4-di(ethoxycarbonyl)phenyl)acetamide (912806-24-7) → 4-[[6-(3,5-bis-decyloxy-phenoxy)-hexanoyl]-(4-methoxycarbonyl-phenyl)-amino]-phthalic acid dimethyl ester (875211-06-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 81 percent / methanol / 1.5 h / Heating

2.1: sodium hydride / dibutyl ether / 2 h / 20 °C

2.2: 85 percent / dibutyl ether / 4 h / Heating

3.1: 43 percent / potassium carbonate; n-Bu₄NI / cyclohexanone / 5 h / Heating

With tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; In methanol; dibutyl ether; cyclohexanone;

DOI:10.1021/jm060468y

upstream raw materials:

6-bromohexanoic acid N-(4-methoxycarbonylphenyl)-N-(3,4-di(methoxycarbonyl)phenyl)amide

3,5-didecyloxyphenol

N-(4-methoxycarbonylphenyl)-N-(3,4-di(methoxycarbonyl)phenyl)amine

N-(4-ethoxycarbonylphenyl)-N-(3,4-di(ethoxycarbonyl)phenyl)acetamide