3-[4-(Azidomethyl)-3-methoxyphenyl]-3-(trifluoromethyl)diazirine

Base Information

Chemical Name:3-[4-(Azidomethyl)-3-methoxyphenyl]-3-(trifluoromethyl)diazirine
CAS No.:875314-84-4
Molecular Formula:C10H8F3N5O
Molecular Weight:271.202
Hs Code.:
DSSTox Substance ID:DTXSID00468000
Nikkaji Number:J2.239.157G

Synonyms:875314-84-4;AGN-PC-00AT2M;DTXSID00468000

Suppliers and Price of 3-[4-(Azidomethyl)-3-methoxyphenyl]-3-(trifluoromethyl)diazirine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 3-[4-(Azidomethyl)-3-methoxyphenyl]-3-(trifluoromethyl)diazirine

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:271.06809438
Heavy Atom Count:19
Complexity:412

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)C2(N=N2)C(F)(F)F)CN=[N+]=[N-]

Technology Process of 3-[4-(Azidomethyl)-3-methoxyphenyl]-3-(trifluoromethyl)diazirine

There total 1 articles about 3-[4-(Azidomethyl)-3-methoxyphenyl]-3-(trifluoromethyl)diazirine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 205485-30-9
3-(4-Bromomethyl-3-methoxy-phenyl)-3-trifluoromethyl-3H-diazirine

: 875314-84-4
3-(4-azidomethyl-3-methoxy)-3-trifluoromethyl-3H-diazirine

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 20 ℃; for 6h;
DOI:10.1248/cpb.53.1510

Reference yield:

: 875314-84-4
3-(4-azidomethyl-3-methoxy)-3-trifluoromethyl-3H-diazirine

: 3-N-[2-methoxy-4-(3-trifluoromethyl-2-d3-methoxy-2-d-3-yl)benzyl]aminocarbonyl-4-(diphenylphosphinyl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 0.33 h / UV-irradiation

2: 2.9 mg / tetrahydrofuran; H₂O

In tetrahydrofuran; water; 2: Staudinger-Bertozzi ligation;
DOI:10.1248/cpb.53.1510