3H-Diazirine, 3-[4-(bromomethyl)-3-methoxyphenyl]-3-(trifluoromethyl)-

Base Information

Chemical Name:3H-Diazirine, 3-[4-(bromomethyl)-3-methoxyphenyl]-3-(trifluoromethyl)-
CAS No.:205485-30-9
Molecular Formula:C10H8BrF3N2O
Molecular Weight:309.086
Hs Code.:
DSSTox Substance ID:DTXSID60451453
Nikkaji Number:J929.127J

Synonyms:205485-30-9;3H-Diazirine, 3-[4-(bromomethyl)-3-methoxyphenyl]-3-(trifluoromethyl)-;DTXSID60451453;2-Methoxy-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzyl bromide

Suppliers and Price of 3H-Diazirine, 3-[4-(bromomethyl)-3-methoxyphenyl]-3-(trifluoromethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3H-Diazirine, 3-[4-(bromomethyl)-3-methoxyphenyl]-3-(trifluoromethyl)-

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:307.97721
Heavy Atom Count:17
Complexity:315

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)C2(N=N2)C(F)(F)F)CBr

Technology Process of 3H-Diazirine, 3-[4-(bromomethyl)-3-methoxyphenyl]-3-(trifluoromethyl)-

There total 9 articles about 3H-Diazirine, 3-[4-(bromomethyl)-3-methoxyphenyl]-3-(trifluoromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 205485-29-6
[2-Methoxy-4-(3-trifluoromethyl-3H-diazirin-3-yl)-phenyl]-methanol

: 205485-30-9
3-(4-Bromomethyl-3-methoxy-phenyl)-3-trifluoromethyl-3H-diazirine

Guidance literature:: With carbon tetrabromide; triphenylphosphine; In diethyl ether;
DOI:10.1055/s-2005-923595

Reference yield:

: 205485-24-1
3-(3-methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine

: 205485-30-9
3-(4-Bromomethyl-3-methoxy-phenyl)-3-trifluoromethyl-3H-diazirine

Guidance literature:: Multi-step reaction with 3 steps

1: 62 percent / TiCl₄ / CH₂Cl₂

2: 91 percent / NaBH₄

3: 90 percent / PPh₃; CBr₄ / diethyl ether

With sodium tetrahydroborate; carbon tetrabromide; titanium tetrachloride; triphenylphosphine; In diethyl ether; dichloromethane; 1: Friedel-Crafts alkylation;
DOI:10.1055/s-2005-923595

Reference yield:

: 205485-25-2
2-methoxy-4-<3-trifluoromethyl-3H-diazirin-3-yl>benzaldehyde

: 205485-30-9
3-(4-Bromomethyl-3-methoxy-phenyl)-3-trifluoromethyl-3H-diazirine

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / NaBH₄

2: 90 percent / PPh₃; CBr₄ / diethyl ether

With sodium tetrahydroborate; carbon tetrabromide; triphenylphosphine; In diethyl ether;
DOI:10.1055/s-2005-923595